Architecture of the Tracheobronchial Tree

Kent E Pinkerton; Laura S. Van Winkle; Charles Plopper; Suzette Smiley-Jewell; Elvira C. Covarrubias; John T. McBride

doi:10.1016/B978-0-12-404577-4.00004-7

Architecture of the Tracheobronchial Tree

Kent E Pinkerton, Laura S. Van Winkle, Charles Plopper, Suzette Smiley-Jewell, Elvira C. Covarrubias, John T. McBride

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

The structure of the mammalian tracheobronchial tree fulfills a number of important and occasionally contradictory requirements. The geometry of the complex system of branching airways allows for efficient transport of gas to and from the lung periphery, while occupying a minimum of volume within the neck and thorax. Individual airways are adequately stiff to sustain the high airflows necessary for extremes of exertion but adequately compliant to narrow during coughing and to permit the removal of accumulated mucus and debris. In addition, bronchial architecture is a major determinant of the pattern of deposition of inhaled particles, a function with important implications for health and disease.

Original language	English (US)
Title of host publication	Comparative Biology of the Normal Lung: Second Edition
Publisher	Elsevier Inc.
Pages	33-51
Number of pages	19
ISBN (Print)	9780124045774, 9780124047266
DOIs	https://doi.org/10.1016/B978-0-12-404577-4.00004-7
State	Published - Mar 18 2015

Keywords

Airway geometry
Airways
Asymmetric airways
Bronchial tree
HRCT
Intralobar airway
Microdissection
Morphometry
Parenchyma
Symmetric airways
Trachea

ASJC Scopus subject areas

Medicine(all)
Pharmacology, Toxicology and Pharmaceutics(all)

Access to Document

10.1016/B978-0-12-404577-4.00004-7

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Cite this

Pinkerton, K. E., Van Winkle, L. S., Plopper, C., Smiley-Jewell, S., Covarrubias, E. C., & McBride, J. T. (2015). Architecture of the Tracheobronchial Tree. In Comparative Biology of the Normal Lung: Second Edition (pp. 33-51). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-404577-4.00004-7

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AU - Van Winkle, Laura S.

AU - Plopper, Charles

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AU - Covarrubias, Elvira C.

AU - McBride, John T.

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