Abstract
The structure of the mammalian tracheobronchial tree fulfills a number of important and occasionally contradictory requirements. The geometry of the complex system of branching airways allows for efficient transport of gas to and from the lung periphery, while occupying a minimum of volume within the neck and thorax. Individual airways are adequately stiff to sustain the high airflows necessary for extremes of exertion but adequately compliant to narrow during coughing and to permit the removal of accumulated mucus and debris. In addition, bronchial architecture is a major determinant of the pattern of deposition of inhaled particles, a function with important implications for health and disease.
| Original language | English (US) |
|---|---|
| Title of host publication | Comparative Biology of the Normal Lung: Second Edition |
| Publisher | Elsevier Inc. |
| Pages | 33-51 |
| Number of pages | 19 |
| ISBN (Print) | 9780124045774, 9780124047266 |
| DOIs | |
| State | Published - Mar 18 2015 |
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Keywords
- Airway geometry
- Airways
- Asymmetric airways
- Bronchial tree
- HRCT
- Intralobar airway
- Microdissection
- Morphometry
- Parenchyma
- Symmetric airways
- Trachea
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
Architecture of the Tracheobronchial Tree. / Pinkerton, Kent E; Van Winkle, Laura S.; Plopper, Charles; Smiley-Jewell, Suzette; Covarrubias, Elvira C.; McBride, John T.
Comparative Biology of the Normal Lung: Second Edition. Elsevier Inc., 2015. p. 33-51.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Architecture of the Tracheobronchial Tree
AU - Pinkerton, Kent E
AU - Van Winkle, Laura S.
AU - Plopper, Charles
AU - Smiley-Jewell, Suzette
AU - Covarrubias, Elvira C.
AU - McBride, John T.
PY - 2015/3/18
Y1 - 2015/3/18
N2 - The structure of the mammalian tracheobronchial tree fulfills a number of important and occasionally contradictory requirements. The geometry of the complex system of branching airways allows for efficient transport of gas to and from the lung periphery, while occupying a minimum of volume within the neck and thorax. Individual airways are adequately stiff to sustain the high airflows necessary for extremes of exertion but adequately compliant to narrow during coughing and to permit the removal of accumulated mucus and debris. In addition, bronchial architecture is a major determinant of the pattern of deposition of inhaled particles, a function with important implications for health and disease.
AB - The structure of the mammalian tracheobronchial tree fulfills a number of important and occasionally contradictory requirements. The geometry of the complex system of branching airways allows for efficient transport of gas to and from the lung periphery, while occupying a minimum of volume within the neck and thorax. Individual airways are adequately stiff to sustain the high airflows necessary for extremes of exertion but adequately compliant to narrow during coughing and to permit the removal of accumulated mucus and debris. In addition, bronchial architecture is a major determinant of the pattern of deposition of inhaled particles, a function with important implications for health and disease.
KW - Airway geometry
KW - Airways
KW - Asymmetric airways
KW - Bronchial tree
KW - HRCT
KW - Intralobar airway
KW - Microdissection
KW - Morphometry
KW - Parenchyma
KW - Symmetric airways
KW - Trachea
UR - http://www.scopus.com/inward/record.url?scp=84939618025&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84939618025&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-404577-4.00004-7
DO - 10.1016/B978-0-12-404577-4.00004-7
M3 - Chapter
AN - SCOPUS:84939618025
SN - 9780124045774
SN - 9780124047266
SP - 33
EP - 51
BT - Comparative Biology of the Normal Lung: Second Edition
PB - Elsevier Inc.
ER -