A randomized comparison between diazepam in aqueous form and in fatty emulsion was performed in Chinese patients undergoing upper gastrointestinal endoscopy. One hundred and eighty-four patients completed the study. The sedative effect is similar with both preparations. Aqueous diazepam caused significantly more pain on injection (75%) and more late venous complication (41%) than the emulsified form (13% and 9% respectively). Thrombosis and thrombophlebitis frequently extended beyond the site of injection. Diazepam in emulsion form caused significantly less venous complications and is therefore superior to the aqueous form for intravenous use.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of gastroenterology and hepatology|
|State||Published - 1988|
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