Abstract
A randomized comparison between diazepam in aqueous form and in fatty emulsion was performed in Chinese patients undergoing upper gastrointestinal endoscopy. One hundred and eighty-four patients completed the study. The sedative effect is similar with both preparations. Aqueous diazepam caused significantly more pain on injection (75%) and more late venous complication (41%) than the emulsified form (13% and 9% respectively). Thrombosis and thrombophlebitis frequently extended beyond the site of injection. Diazepam in emulsion form caused significantly less venous complications and is therefore superior to the aqueous form for intravenous use.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 127-131 |
| Number of pages | 5 |
| Journal | Journal of gastroenterology and hepatology |
| Volume | 3 |
| Issue number | 2 |
| State | Published - 1988 |
| Externally published | Yes |
ASJC Scopus subject areas
- Gastroenterology
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Chung, S. C. S., & Leung, J. (1988). Aqueous or emulsified diazepam in upper endoscopy: A randomized trial. Journal of gastroenterology and hepatology, 3(2), 127-131.