Arterial obstruction due to intimal myproliferation is an outcome used for investigating chronic allograft vasculopathy in animal models. Since harvested tissue may be distorted while processing, discrepancy may happen in the measure of the obstruction. We propose a standardized micromorphometric method for calculating the percentage of obstruction with eliminating the variability in the shape of the vessel cross-section. The mathematical adjustment avoids the overestimation of the percentage of obstruction and improves accuracy.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Aug 2005|
- Chronic allograft vasculopathy
- Standardized obstruction percentage: Rat aorta
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine