Applications of functional protein microarrays: identifying protein-protein interactions in an array format.

Matthew A Coleman, Peter T. Beernink, Julio A. Camarero, Joanna S. Albala

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The use of protein arrays and their importance in proteomic applications continues to be at the forefront of scientific discovery and innovative technology development. To date, array-based approaches have proven to be a powerful tool for protein expression profiling, novel biomarker discovery, and the examination of protein, DNA, and small molecule interactions. Our laboratory has developed several approaches for characterizing protein-protein interactions using protein microarrays for a variety of different biological applications. Here we describe the identification of protein-protein interactions using a microarray format.

Original languageEnglish (US)
Pages (from-to)121-130
Number of pages10
JournalMethods in molecular biology (Clifton, N.J.)
Volume385
StatePublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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