Application of diagnostic tests in veterinary epidemiologic studies

M. Greiner, Ian Gardner

Research output: Contribution to journalArticle

137 Citations (Scopus)

Abstract

Important applications of diagnostic tests in non-clinical areas of veterinary medicine include surveillance, monitoring or screening for disease, prevalence estimation, and risk-factor studies. In this review, we address the processing and analysis of diagnostic data with special emphasis on serological data from enzyme-linked immunosorbent assays (ELISAs). We describe methods that are used to adjust for misclassification (imperfect sensitivity and specificity) in the different applications of diagnostic tests. These methods often have limitations attributable to the uncertainty of sensitivity and specificity estimates. We review descriptive and analytical statistical methods that allow adequate presentation of non-clinical diagnostic data. (C) 2000 Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)43-59
Number of pages17
JournalPreventive Veterinary Medicine
Volume45
Issue number1-2
DOIs
StatePublished - May 30 2000

Fingerprint

Routine Diagnostic Tests
diagnostic techniques
epidemiological studies
Epidemiologic Studies
monitoring
disease prevalence
veterinary medicine
Sensitivity and Specificity
Veterinary Medicine
risk factors
statistical analysis
uncertainty
enzyme-linked immunosorbent assay
screening
Uncertainty
Enzyme-Linked Immunosorbent Assay
methodology

Keywords

  • Diagnostic tests
  • Epidemiology
  • Misclassification
  • Sensitivity
  • Specificity

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology

Cite this

Application of diagnostic tests in veterinary epidemiologic studies. / Greiner, M.; Gardner, Ian.

In: Preventive Veterinary Medicine, Vol. 45, No. 1-2, 30.05.2000, p. 43-59.

Research output: Contribution to journalArticle

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