Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head

Robert Zawadzki, Yan Zhang, Steven M. Jones, Stacey S. Choi, Barry Cense, Diana Chen, Alfred R. Fuller, Donald T. Miller, Scot S. Olivier, John S Werner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Two deformable mirrors (2DM) were used in an adaptive optics - optical coherence tomography (AO-OCT) system to image in vivo microscopic retinal structures of healthy and diseased retinas. As a result, multiple morphological structures not previously seen in vivo have been visualized. Among those presented are three-dimensional representations of the fovea and optic nerve head (ONH), revealing cellular structures and micro-vasculature. Drusen in macular degeneration and photoreceptor dystrophies are also presented. Different methods for displaying volumetric AO-OCT data to facilitate visualization of certain morphological details are compared.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6426
DOIs
StatePublished - 2007
EventOphthalmic Technologies XVII - San Jose, CA, United States
Duration: Jan 20 2007Jan 23 2007

Other

OtherOphthalmic Technologies XVII
CountryUnited States
CitySan Jose, CA
Period1/20/071/23/07

Fingerprint

Adaptive optics
Optical tomography
Optics
Imaging techniques
Visualization

Keywords

  • (010.1080) adaptive optics
  • (110.4500) optical coherence tomography
  • (120.3890) medical optics instrumentation
  • (170.0110) imaging system
  • (170.4470) ophthalmology
  • (220.1000) aberration compensation

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Zawadzki, R., Zhang, Y., Jones, S. M., Choi, S. S., Cense, B., Chen, D., ... Werner, J. S. (2007). Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6426). [64261O] https://doi.org/10.1117/12.701512

Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head. / Zawadzki, Robert; Zhang, Yan; Jones, Steven M.; Choi, Stacey S.; Cense, Barry; Chen, Diana; Fuller, Alfred R.; Miller, Donald T.; Olivier, Scot S.; Werner, John S.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6426 2007. 64261O.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zawadzki, R, Zhang, Y, Jones, SM, Choi, SS, Cense, B, Chen, D, Fuller, AR, Miller, DT, Olivier, SS & Werner, JS 2007, Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6426, 64261O, Ophthalmic Technologies XVII, San Jose, CA, United States, 1/20/07. https://doi.org/10.1117/12.701512
Zawadzki R, Zhang Y, Jones SM, Choi SS, Cense B, Chen D et al. Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6426. 2007. 64261O https://doi.org/10.1117/12.701512
Zawadzki, Robert ; Zhang, Yan ; Jones, Steven M. ; Choi, Stacey S. ; Cense, Barry ; Chen, Diana ; Fuller, Alfred R. ; Miller, Donald T. ; Olivier, Scot S. ; Werner, John S. / Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6426 2007.
@inproceedings{8334a2a726224fdea4de03451d268092,
title = "Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head",
abstract = "Two deformable mirrors (2DM) were used in an adaptive optics - optical coherence tomography (AO-OCT) system to image in vivo microscopic retinal structures of healthy and diseased retinas. As a result, multiple morphological structures not previously seen in vivo have been visualized. Among those presented are three-dimensional representations of the fovea and optic nerve head (ONH), revealing cellular structures and micro-vasculature. Drusen in macular degeneration and photoreceptor dystrophies are also presented. Different methods for displaying volumetric AO-OCT data to facilitate visualization of certain morphological details are compared.",
keywords = "(010.1080) adaptive optics, (110.4500) optical coherence tomography, (120.3890) medical optics instrumentation, (170.0110) imaging system, (170.4470) ophthalmology, (220.1000) aberration compensation",
author = "Robert Zawadzki and Yan Zhang and Jones, {Steven M.} and Choi, {Stacey S.} and Barry Cense and Diana Chen and Fuller, {Alfred R.} and Miller, {Donald T.} and Olivier, {Scot S.} and Werner, {John S}",
year = "2007",
doi = "10.1117/12.701512",
language = "English (US)",
isbn = "0819465399",
volume = "6426",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head

AU - Zawadzki, Robert

AU - Zhang, Yan

AU - Jones, Steven M.

AU - Choi, Stacey S.

AU - Cense, Barry

AU - Chen, Diana

AU - Fuller, Alfred R.

AU - Miller, Donald T.

AU - Olivier, Scot S.

AU - Werner, John S

PY - 2007

Y1 - 2007

N2 - Two deformable mirrors (2DM) were used in an adaptive optics - optical coherence tomography (AO-OCT) system to image in vivo microscopic retinal structures of healthy and diseased retinas. As a result, multiple morphological structures not previously seen in vivo have been visualized. Among those presented are three-dimensional representations of the fovea and optic nerve head (ONH), revealing cellular structures and micro-vasculature. Drusen in macular degeneration and photoreceptor dystrophies are also presented. Different methods for displaying volumetric AO-OCT data to facilitate visualization of certain morphological details are compared.

AB - Two deformable mirrors (2DM) were used in an adaptive optics - optical coherence tomography (AO-OCT) system to image in vivo microscopic retinal structures of healthy and diseased retinas. As a result, multiple morphological structures not previously seen in vivo have been visualized. Among those presented are three-dimensional representations of the fovea and optic nerve head (ONH), revealing cellular structures and micro-vasculature. Drusen in macular degeneration and photoreceptor dystrophies are also presented. Different methods for displaying volumetric AO-OCT data to facilitate visualization of certain morphological details are compared.

KW - (010.1080) adaptive optics

KW - (110.4500) optical coherence tomography

KW - (120.3890) medical optics instrumentation

KW - (170.0110) imaging system

KW - (170.4470) ophthalmology

KW - (220.1000) aberration compensation

UR - http://www.scopus.com/inward/record.url?scp=34548290985&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548290985&partnerID=8YFLogxK

U2 - 10.1117/12.701512

DO - 10.1117/12.701512

M3 - Conference contribution

AN - SCOPUS:34548290985

SN - 0819465399

SN - 9780819465399

VL - 6426

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -