Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head

Robert Zawadzki, Yan Zhang, Steven M. Jones, Stacey S. Choi, Barry Cense, Diana Chen, Alfred R. Fuller, Donald T. Miller, Scot S. Olivier, John S Werner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Two deformable mirrors (2DM) were used in an adaptive optics - optical coherence tomography (AO-OCT) system to image in vivo microscopic retinal structures of healthy and diseased retinas. As a result, multiple morphological structures not previously seen in vivo have been visualized. Among those presented are three-dimensional representations of the fovea and optic nerve head (ONH), revealing cellular structures and micro-vasculature. Drusen in macular degeneration and photoreceptor dystrophies are also presented. Different methods for displaying volumetric AO-OCT data to facilitate visualization of certain morphological details are compared.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6426
DOIs
StatePublished - 2007
EventOphthalmic Technologies XVII - San Jose, CA, United States
Duration: Jan 20 2007Jan 23 2007

Other

OtherOphthalmic Technologies XVII
CountryUnited States
CitySan Jose, CA
Period1/20/071/23/07

Keywords

  • (010.1080) adaptive optics
  • (110.4500) optical coherence tomography
  • (120.3890) medical optics instrumentation
  • (170.0110) imaging system
  • (170.4470) ophthalmology
  • (220.1000) aberration compensation

ASJC Scopus subject areas

  • Engineering(all)

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    Zawadzki, R., Zhang, Y., Jones, S. M., Choi, S. S., Cense, B., Chen, D., Fuller, A. R., Miller, D. T., Olivier, S. S., & Werner, J. S. (2007). Application of adaptive optics - Optical Coherence Tomography for in vivo imaging of microscopic structures in the retina and optic nerve head. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6426). [64261O] https://doi.org/10.1117/12.701512