Preincubation with alkaline phosphatase stimulated the activity of ammonium sulfate precipitated phosphatidic acid phosphatase from rat liver cytosol. Treatment with Mg-ATP inhibited the activity. The possibility is discussed that the soluble phosphatidic acid phosphatase, assumed to catalyze the rate-limiting step in the biosynthesis of triglycerides, is to some extent regulated by phosphorylation - dephosphorylation.
|Original language||English (US)|
|Number of pages||8|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Mar 15 1982|
ASJC Scopus subject areas
- Molecular Biology