Antioxidants, Oxyrase, and mitochondrial uncoupler 2,4-dinitrophenol improved postthaw survival of rhesus monkey sperm from ejaculates with low cryosurvival

Qiaoxiang Dong, Theodore L Tollner, Sarah E. Rodenburg, Dana L. Hill, Catherine A. Vandevoort

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Various antioxidant strategies such as supplementation of antioxidants, limiting oxygen concentration with Oxyrase, and reducing reactive oxygen species through mild mitochondrial uncoupling had statistically significant beneficial effects on sperm cryopreservation from rhesus monkeys with low cryoresistant ejaculates. Individuals or species that have higher sensitivity to cryodamage may derive the most benefit from these treatments.

Original languageEnglish (US)
Pages (from-to)2359-2361
Number of pages3
JournalFertility and Sterility
Volume94
Issue number6
DOIs
StatePublished - Nov 2010

Keywords

  • Electron transport
  • Macaca mulatta
  • reactive oxygen species
  • semen

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

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