Abstract
Cardiovascular disease is the leading cause of morbidity and mortality in Western populations. Several lines of evidence support the role of oxidative stress in atherogenesis. Dietary micronutrients with antioxidant properties and vitamins have also been shown to have a benefit with regards to cardiovascular disease. The most persuasive evidence relates to alpha tocopherol and folate and vitamin B(12). Although the evidence is mounting for supplementation with alpha tocopherol and folate and B(12) for secondary prevention of cardiovascular disease, no clear consensus can be reached for primary prevention of cardiovascular disease. This will have to await results of ongoing clinical trials.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 342-351 |
| Number of pages | 10 |
| Journal | Current Atherosclerosis Reports |
| Volume | 2 |
| Issue number | 4 |
| State | Published - Jul 2000 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Antioxidants and vitamins to reduce cardiovascular disease. / Devaraj, S.; Jialal, I.
In: Current Atherosclerosis Reports, Vol. 2, No. 4, 07.2000, p. 342-351.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antioxidants and vitamins to reduce cardiovascular disease.
AU - Devaraj, S.
AU - Jialal, I.
PY - 2000/7
Y1 - 2000/7
N2 - Cardiovascular disease is the leading cause of morbidity and mortality in Western populations. Several lines of evidence support the role of oxidative stress in atherogenesis. Dietary micronutrients with antioxidant properties and vitamins have also been shown to have a benefit with regards to cardiovascular disease. The most persuasive evidence relates to alpha tocopherol and folate and vitamin B(12). Although the evidence is mounting for supplementation with alpha tocopherol and folate and B(12) for secondary prevention of cardiovascular disease, no clear consensus can be reached for primary prevention of cardiovascular disease. This will have to await results of ongoing clinical trials.
AB - Cardiovascular disease is the leading cause of morbidity and mortality in Western populations. Several lines of evidence support the role of oxidative stress in atherogenesis. Dietary micronutrients with antioxidant properties and vitamins have also been shown to have a benefit with regards to cardiovascular disease. The most persuasive evidence relates to alpha tocopherol and folate and vitamin B(12). Although the evidence is mounting for supplementation with alpha tocopherol and folate and B(12) for secondary prevention of cardiovascular disease, no clear consensus can be reached for primary prevention of cardiovascular disease. This will have to await results of ongoing clinical trials.
UR - http://www.scopus.com/inward/record.url?scp=0034230589&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034230589&partnerID=8YFLogxK
M3 - Article
C2 - 11122764
AN - SCOPUS:0034230589
VL - 2
SP - 342
EP - 351
JO - Current Atherosclerosis Reports
JF - Current Atherosclerosis Reports
SN - 1523-3804
IS - 4
ER -