Antihistamines in the management of canine atopic dermatitis

A retrospective study of 171 dogs (1992-1998)

Gila Zur, Peter Ihrke, Stephen D White, Philip H Kass

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Antihistamines were prescribed for 178 of 271 dogs with a diagnosis of atopic dermatitis at the Veterinary Medical Teaching Hospital of the University of California, Davis from 1992 to 1998. Fifty-four percent of 166 dogs given antihistamines responded favorably to these treatments, with 27% of the responses rated as good and 27% rated as moderate. Diphenhydramine and hydroxyzine were the most commonly used antihistamines and were the most frequently effective. Chlorpheniramine and clemastine were administered less frequently and had much lower positive response rates. Responses to antihistamines as a group were significantly better in dogs having onset of clinical signs at younger ages (odds ratios for 1-year increase in age = 0.72, 95% confidence interval = 0.57 to 0.91, P = .005). INTRODUCTION

Original languageEnglish (US)
JournalVeterinary Therapeutics
Volume3
Issue number1
StatePublished - 2002

Fingerprint

antihistamines
atopic dermatitis
Histamine Antagonists
Atopic Dermatitis
retrospective studies
Canidae
Retrospective Studies
Dogs
dogs
Clemastine
Hydroxyzine
Chlorpheniramine
Diphenhydramine
Teaching Hospitals
odds ratio
confidence interval
Odds Ratio
Confidence Intervals

ASJC Scopus subject areas

  • veterinary(all)

Cite this

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