Antigenic and nucleotide characterization of a herpesvirus isolated from Pacific harbor seals (Phoca vitulina richardsii)

D. P. King, R. Parselles, F. M D Gulland, J. M. Lapointe, Linda J Lowenstine, D. A. Ferrick, Jeffrey L Stott

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

This report describes the antigenic and nucleotide characterization of a herpes-like virus that has been isolated from the adrenal tissues of neonatal Pacific harbor seals. Infection with this virus has been previously implicated as a major cause of death of animals undergoing rehabilitation. Comparison and phylogenetic analysis of sequenced fragments of the DNA polymerase, glycoprotein B and glycoprotein D genes, and immunofluorescence assay using herpesvirus-specific monoclonal antibodies, demonstrated close similarity of the Pacific harbor seal herpesvirus to European isolates of phocid herpesvirus-1 (PHV-1) and other α-herpesviruses affecting terrestrial carnivores.

Original languageEnglish (US)
Pages (from-to)2021-2027
Number of pages7
JournalArchives of Virology
Volume143
Issue number10
DOIs
StatePublished - 1998

Fingerprint

Phoca
Herpesviridae
Nucleotides
Glycoproteins
Virus Diseases
DNA-Directed DNA Polymerase
Fluorescent Antibody Technique
Cause of Death
Rehabilitation
Monoclonal Antibodies
Viruses
Genes

ASJC Scopus subject areas

  • Genetics
  • Applied Microbiology and Biotechnology

Cite this

Antigenic and nucleotide characterization of a herpesvirus isolated from Pacific harbor seals (Phoca vitulina richardsii). / King, D. P.; Parselles, R.; Gulland, F. M D; Lapointe, J. M.; Lowenstine, Linda J; Ferrick, D. A.; Stott, Jeffrey L.

In: Archives of Virology, Vol. 143, No. 10, 1998, p. 2021-2027.

Research output: Contribution to journalArticle

King, D. P. ; Parselles, R. ; Gulland, F. M D ; Lapointe, J. M. ; Lowenstine, Linda J ; Ferrick, D. A. ; Stott, Jeffrey L. / Antigenic and nucleotide characterization of a herpesvirus isolated from Pacific harbor seals (Phoca vitulina richardsii). In: Archives of Virology. 1998 ; Vol. 143, No. 10. pp. 2021-2027.
@article{c4c6153cdab04c528a716577f1ed8758,
title = "Antigenic and nucleotide characterization of a herpesvirus isolated from Pacific harbor seals (Phoca vitulina richardsii)",
abstract = "This report describes the antigenic and nucleotide characterization of a herpes-like virus that has been isolated from the adrenal tissues of neonatal Pacific harbor seals. Infection with this virus has been previously implicated as a major cause of death of animals undergoing rehabilitation. Comparison and phylogenetic analysis of sequenced fragments of the DNA polymerase, glycoprotein B and glycoprotein D genes, and immunofluorescence assay using herpesvirus-specific monoclonal antibodies, demonstrated close similarity of the Pacific harbor seal herpesvirus to European isolates of phocid herpesvirus-1 (PHV-1) and other α-herpesviruses affecting terrestrial carnivores.",
author = "King, {D. P.} and R. Parselles and Gulland, {F. M D} and Lapointe, {J. M.} and Lowenstine, {Linda J} and Ferrick, {D. A.} and Stott, {Jeffrey L}",
year = "1998",
doi = "10.1007/s007050050438",
language = "English (US)",
volume = "143",
pages = "2021--2027",
journal = "Archives of Virology",
issn = "0304-8608",
publisher = "Springer Wien",
number = "10",

}

TY - JOUR

T1 - Antigenic and nucleotide characterization of a herpesvirus isolated from Pacific harbor seals (Phoca vitulina richardsii)

AU - King, D. P.

AU - Parselles, R.

AU - Gulland, F. M D

AU - Lapointe, J. M.

AU - Lowenstine, Linda J

AU - Ferrick, D. A.

AU - Stott, Jeffrey L

PY - 1998

Y1 - 1998

N2 - This report describes the antigenic and nucleotide characterization of a herpes-like virus that has been isolated from the adrenal tissues of neonatal Pacific harbor seals. Infection with this virus has been previously implicated as a major cause of death of animals undergoing rehabilitation. Comparison and phylogenetic analysis of sequenced fragments of the DNA polymerase, glycoprotein B and glycoprotein D genes, and immunofluorescence assay using herpesvirus-specific monoclonal antibodies, demonstrated close similarity of the Pacific harbor seal herpesvirus to European isolates of phocid herpesvirus-1 (PHV-1) and other α-herpesviruses affecting terrestrial carnivores.

AB - This report describes the antigenic and nucleotide characterization of a herpes-like virus that has been isolated from the adrenal tissues of neonatal Pacific harbor seals. Infection with this virus has been previously implicated as a major cause of death of animals undergoing rehabilitation. Comparison and phylogenetic analysis of sequenced fragments of the DNA polymerase, glycoprotein B and glycoprotein D genes, and immunofluorescence assay using herpesvirus-specific monoclonal antibodies, demonstrated close similarity of the Pacific harbor seal herpesvirus to European isolates of phocid herpesvirus-1 (PHV-1) and other α-herpesviruses affecting terrestrial carnivores.

UR - http://www.scopus.com/inward/record.url?scp=0031762697&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031762697&partnerID=8YFLogxK

U2 - 10.1007/s007050050438

DO - 10.1007/s007050050438

M3 - Article

C2 - 9856089

AN - SCOPUS:0031762697

VL - 143

SP - 2021

EP - 2027

JO - Archives of Virology

JF - Archives of Virology

SN - 0304-8608

IS - 10

ER -