Antigenic and nucleotide characterization of a herpesvirus isolated from Pacific harbor seals (Phoca vitulina richardsii)

D. P. King, R. Parselles, F. M D Gulland, J. M. Lapointe, Linda J Lowenstine, D. A. Ferrick, Jeffrey L Stott

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

This report describes the antigenic and nucleotide characterization of a herpes-like virus that has been isolated from the adrenal tissues of neonatal Pacific harbor seals. Infection with this virus has been previously implicated as a major cause of death of animals undergoing rehabilitation. Comparison and phylogenetic analysis of sequenced fragments of the DNA polymerase, glycoprotein B and glycoprotein D genes, and immunofluorescence assay using herpesvirus-specific monoclonal antibodies, demonstrated close similarity of the Pacific harbor seal herpesvirus to European isolates of phocid herpesvirus-1 (PHV-1) and other α-herpesviruses affecting terrestrial carnivores.

Original languageEnglish (US)
Pages (from-to)2021-2027
Number of pages7
JournalArchives of Virology
Volume143
Issue number10
DOIs
StatePublished - 1998

    Fingerprint

ASJC Scopus subject areas

  • Genetics
  • Applied Microbiology and Biotechnology

Cite this