Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans

George Richard Thompson, Nathan P. Wiederhold, Annette W. Fothergill, Ana C. Vallor, Brian L. Wickes, Thomas F. Patterson

Research output: Contribution to journalArticle

93 Scopus citations

Abstract

We measured antifungal activity against 128 cryptococcal isolates (86 of C. neoformans and 42 of C. gattii) to determine if differences in serotype susceptibility exist. Contrary to previous results, we found no serotype susceptibility differences. Isavuconazole, posaconazole, and voriconazole demonstrated excellent potency against each isolate and serotype, including isolates with reduced fluconazole susceptibilities.

Original languageEnglish (US)
Pages (from-to)309-311
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number1
DOIs
StatePublished - Jan 2009
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

Cite this