Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans

George Richard Thompson, Nathan P. Wiederhold, Annette W. Fothergill, Ana C. Vallor, Brian L. Wickes, Thomas F. Patterson

Research output: Contribution to journalArticle

91 Citations (Scopus)

Abstract

We measured antifungal activity against 128 cryptococcal isolates (86 of C. neoformans and 42 of C. gattii) to determine if differences in serotype susceptibility exist. Contrary to previous results, we found no serotype susceptibility differences. Isavuconazole, posaconazole, and voriconazole demonstrated excellent potency against each isolate and serotype, including isolates with reduced fluconazole susceptibilities.

Original languageEnglish (US)
Pages (from-to)309-311
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number1
DOIs
StatePublished - Jan 2009
Externally publishedYes

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Cryptococcus gattii
Cryptococcus neoformans
Fluconazole
Serogroup

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

Cite this

Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans. / Thompson, George Richard; Wiederhold, Nathan P.; Fothergill, Annette W.; Vallor, Ana C.; Wickes, Brian L.; Patterson, Thomas F.

In: Antimicrobial Agents and Chemotherapy, Vol. 53, No. 1, 01.2009, p. 309-311.

Research output: Contribution to journalArticle

Thompson, George Richard ; Wiederhold, Nathan P. ; Fothergill, Annette W. ; Vallor, Ana C. ; Wickes, Brian L. ; Patterson, Thomas F. / Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans. In: Antimicrobial Agents and Chemotherapy. 2009 ; Vol. 53, No. 1. pp. 309-311.
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