Anticoagulation in the elderly

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Oral anticoagulation therapy has demonstrated benefit in the treatment and prevention of a variety of thromboembolic disorders. Most individuals who receive oral anticoagulant therapy are elderly patients with nonvalvular atrial fibrillation and acute or recurrent venous thromboembolism. Anticoagulation in elderly patients poses unique challenges for the practicing clinician because they are simultaneously at higher risk for recurrent thromboembolism and major bleeding, including catastrophic intracranial hemorrhage. The pharmacology of warfarin in the elderly is reviewed, including important drug interactions and current dosing recommendations for elderly patients. Evidence of the benefits and risks of oral anticoagulation therapy are reviewed for patients with atrial fibrillation and venous thromboembolism. This information should enable practitioners to better assess the relative risks and benefit of oral anticoagulation therapy to guide treatment decisions in the elderly.

Original languageEnglish (US)
Pages (from-to)365-370
Number of pages6
JournalCurrent Opinion in Pulmonary Medicine
Issue number5
StatePublished - 2001

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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