Anticipation of conflict monitoring in the anterior cingulate cortex and the prefrontal cortex

Myeong Ho Sohn, Mark V. Albert, Kwanjin Jung, Cameron S Carter, John R. Anderson

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

The anterior cingulate cortex (ACC) has been suggested as a monitoring center that is responsible for online detection of response conflicts. In this view, the conflict signal detected by the ACC is transmitted to other brain regions, such as the dorsal part of the lateral prefrontal cortex (IPFC), to increase the level of cognitive control. In this functional MRI (fMRI) study, we examined the conflict resolution that goes beyond online detection of response conflicts. Participants learned pseudoarithmetic problem-solving tasks that involve stimulus-response mapping rules with high or low conflicts. On half of the trials, participants had a preview of the upcoming operator that allowed advance preparation for the mapping rules. The preview significantly reduced the conflict effects on latency. During the preview, both the ACC and IPFC were activated in anticipation of conflict, and this anticipatory activation was highly predictive of the subsequent latency. These results suggest that the ACC and IPFC are responsible for both anticipatory preparation and online adjustment in response to conflicts. The results also confirm the roles of the IPFC and ACC in managing conflict during problem solving and extend these roles to include responding to anticipation of conflicts that may arise between incompatible stimulus-response mappings maintained in working memory during preparation.

Original languageEnglish (US)
Pages (from-to)10330-10334
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume104
Issue number25
DOIs
StatePublished - Jun 19 2007

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Gyrus Cinguli
Prefrontal Cortex
Social Adjustment
Conflict (Psychology)
Negotiating
Short-Term Memory
Magnetic Resonance Imaging
Brain

Keywords

  • Lateral prefrontal cortex
  • Preparation
  • Problem solving

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

Anticipation of conflict monitoring in the anterior cingulate cortex and the prefrontal cortex. / Sohn, Myeong Ho; Albert, Mark V.; Jung, Kwanjin; Carter, Cameron S; Anderson, John R.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 25, 19.06.2007, p. 10330-10334.

Research output: Contribution to journalArticle

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