Anti-retinal antibodies in Vitamin A deficiency

Michael P. Ellis, Melinda Y. Chang, Glenn Yiu

Research output: Contribution to journalArticlepeer-review


Vitamin A is an important component of the visual cycle, and its deficiency causes a retinal degeneration that may be reversed with retinol supplementation. Here, the authors present a patient with vitamin A deficiency and rod-mediated retinopathy who was found to have multiple anti-retinal antibodies that gradually dissipated after vitamin A supplementation. This interesting case suggests the possibility that the photoreceptor degeneration induced by vitamin A deficiency may lead to transient immune exposure to retinal antigens and development of anti-retinal antibodies.

Original languageEnglish (US)
Pages (from-to)723-726
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number12
StatePublished - Dec 2020

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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