Antemortem diagnosis of cystic endometrial hyperplasia and successful ovariohysterectomy in an african warthog (phacochoerus africanus)

Kimberly A. Thompson, Andrew Niehaus, Wynona Shellabarger, Sarah Depenbrock, Dalen Agnew

Research output: Contribution to journalArticle

2 Scopus citations


During a routine geriatric examination on a 9-yr-old, nulliparous female African warthog (Phacochoerus africanus), a severely enlarged, mixed echogenicity uterus was discovered during transabdominal ultrasound. Ovariohysterectomy (OVH) was elected and performed due to concern for a potential neoplastic condition. Postoperatively, the warthog was treated prophylactically with metoclopramide and ranitidine to promote gastrointestinal motility and prevent postoperative ileus. The gross appearance and histopathology confirmed the presence of extensive widely disseminated cystic changes consistent with cystic endometrial hyperplasia (CEH) and multiple para-ovarian cysts. Uterine pathology, including CEH, is a common condition in domestic potbellied pigs (Sus scrofa), and as a result, it is recommended to perform an OVH at an early age. The advanced uterine changes may have accounted for this animal's history of infertility. This case provides evidence that nulliparity may be associated with the development of uterine pathology in warthogs. Increased knowledge of reproductive pathology will aid in improved management strategies for breeding nondomestic suids.

Original languageEnglish (US)
Pages (from-to)904-908
Number of pages5
JournalJournal of Zoo and Wildlife Medicine
Issue number4
StatePublished - Dec 1 2015
Externally publishedYes



  • Cystic endometrial hyperplasia
  • ovariohysterectomy
  • Phacochoerus africanus
  • suid
  • warthog

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this