Threshold vs radiance (tvr) functions and the loci of spectral unique blue and unique green were measured for six diabetic subjects and four age-matched controls. The tvr functions provided an indication of cone-sensitivity losses of diabetics compared to controls, while the unique hue loci were used to assess relative cone contributions to chromatic-opponent pathways. If the sensitivity losses of S-cone pathways observed in diabetic subjects were due only to anomalies before the sites of chromatic opponency, current models of chromatic pathways would predict that unique blue and unique green should be shifted towards shorter wavelengths relative to control subjects. With one exception, the unique hue loci for all tested diabetic subjects, including those with relatively large sensitivity losses of their short-wavelength-sensitivity (S-) cone pathways, fell within the range of unique hue loci for the controls. The results are consistent with the hypothesis that diabetes produces a defect beyond the sites that encode the sensations of unique blue and unique green within chromatically-opponent pathways.
|Original language||English (US)|
|Number of pages||10|
|Journal||Clinical Vision Sciences|
|State||Published - 1991|
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