Angular deformity of the lower extremity in children with renal osteodystrophy

Jon Davids, R. Fisher, G. Lum, S. Von Glinski

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


We have treated 15 children with end-stage renal disease (ESRD), renal osteodystrophy, and genu valgum in the last 22 years. In a retrospective review, we determined that periods of metabolic instability, best characterized as an alkaline phosphatase of 500 U for at least 10 months, were associated with progression of deformity. Histomorphometric bone biopsy provided information that proved essential for effective evaluation and treatment in this group. Complications of corrective osteotomy were related to perioperative metabolic instability. A surgical treatment protocol is described, emphasizing preoperative assessment by histomorphometric bone biopsy and multimodal medical management to maintain metabolic stability perioperatively.

Original languageEnglish (US)
Pages (from-to)291-299
Number of pages9
JournalJournal of Pediatric Orthopaedics
Issue number3
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Pediatrics, Perinatology, and Child Health
  • Surgery


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