It may be concluded from this study that arteries affected by carcinoma characteristically appear irregularly stenosed. The changes are usually localized, unless the tumour is large, in which case the vascular changes may be marked. The arterial involvement in inflammatory disease, on the other hand, has a smooth regular appearance. The involvement is more often generalized and several extrapancreatic arteries may then be affected. Tumour vessels, being newly formed, are markedly deranged and appear different from the smooth regular lumen variations seen in inflammatory disease. Moreover, tumour vessels usually occur within the usually small area corresponding to the tumour, while inflammatory changes are more disseminated. The displacement of vessels in pancreatitis is smooth and arch shaped but in carcinoma it is usually less marked and more abrupt and irregular. Venous lesions occur frequently in carcinoma as well as in inflammatory disease and do not permit differentiation. Difficulties in differentiation may appear when changes caused by inflammatory and malignant disease occur simultaneously and in the presence of localized arterial irregularities, corresponding to circumscribed pancreatitis. With increasing experience, however, the difficulties seldom arise. It should be realized that there can be tumours, even large ones, which with present technique and skill may not be diagnosed. Angiography, however, affords great help in the diagnosis of pancreatic disease.
|Original language||English (US)|
|State||Published - Jan 1 1972|
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