Angiographic film subtraction using a laser digitizer and computer processing

John M Boone, Neva M. Corrigan, Stephen T. Hecht, Daniel P Link

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Digital subtraction angiography has been accepted as an invaluable clinical tool over the past decade; however, film-screen-based angiography is still performed routinely when high-resolution or large field-of-view angiograms are needed. A technique is presented whereby two films from an angiographic sequence are digitized using a high-resolution laser digitizer, and the digitized images are aligned, subtracted, and displayed using the computer. To accommodate for some types of patient motion, an image warping algorithm is presented and discussed in detail. The warping algorithm is piecewise linear, using triangular regions for warping, resulting in a global nonlinear transform across triangle elements. An algorithm describing optimal triangle selection also is discussed. The results show that subtraction images of excellent quality can be produced by the proposed technique, and suggest that, in some settings, digitized subtraction films may be preferred over conventional film subtraction.

Original languageEnglish (US)
Pages (from-to)159-167
Number of pages9
JournalJournal of Digital Imaging
Issue number4
StatePublished - Nov 1998


  • Angiography
  • Digital image processing
  • Film subtraction
  • Image registration
  • Warping algorithm

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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