Anesthetic potency (MAC) of nitrous oxide in the dog, cat, and stump tail monkey

Eugene Steffey, J. R. Gillespie, J. D. Berry, E. I. Eger IInd, E. S. Munson

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


The authors determined that 75% nitrous oxide (N2O) contributed about one third of the minimum (MAC) requirement for anesthesia in dogs, cats, and monkeys (Macaca arctoides). The anesthetic effect of N2O is less than half that reported for man as determined with similar techniques. Nitrous oxide does not contribute significant anesthesia at concentrations which permit normal oxygenation, and therefore should not be used as a sole agent for surgical manipulations in the species studied. Its importance as an adjunct to anesthesia is of limited value.

Original languageEnglish (US)
Pages (from-to)530-532
Number of pages3
JournalUnknown Journal
Issue number5
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)


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