Anaplasma phagocytophilum subverts tick salivary gland proteins

Janet E Foley, Nathan Nieto

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Anaplasma phagocytophilum is a bacterium that is transmitted by Ixodes spp. ticks, in which it resides in salivary glands. Ticks inoculate the pathogen into hosts together with an array of salivary molecules that reduce host anti-tick inflammation. Sukumaran et al. recently showed that A. phagocytophilum uses a tick salivary protein, Salp16, to enhance its uptake from the host and into the salivary gland. Occupation and exploitation of tick salivary glands have implications for the maintenance and detection of A. phagocytophilum in its vector and early pathogen interactions with its hosts.

Original languageEnglish (US)
Pages (from-to)3-5
Number of pages3
JournalTrends in Parasitology
Volume23
Issue number1
DOIs
StatePublished - Jan 2007

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology

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