Analysis of skeletal muscle hypertrophy in models of increased loading

Sue C. Bodine, Keith Baar

Research output: Chapter in Book/Report/Conference proceedingChapter

26 Scopus citations


Skeletal muscle is a highly adaptive tissue that modifies its size in response to a variety of external stimuli. In adult mammals, skeletal muscle hypertrophy occurs primarily as a response to increases in external loading. Here, we describe the methods that should be used for a comprehensive assessment of muscle hypertrophy in animal models. The methods include the measurement of muscle mass, fiber cross-sectional area, contractile function, and protein concentration.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
Number of pages17
StatePublished - 2012

Publication series

NameMethods in Molecular Biology
ISSN (Print)10643745


  • Isometric maximal force
  • Muscle hypertrophy
  • Physiological cross-sectional area
  • Resistance exercise
  • Specific tension

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


Dive into the research topics of 'Analysis of skeletal muscle hypertrophy in models of increased loading'. Together they form a unique fingerprint.

Cite this