Analysis of risk factors associated with complications following mandibulectomy and maxillectomy in dogs

Megan Cray, Laura E. Selmic, Cameron Kindra, Brittany Abrams, Ashton Story, Kaitlan Hovis, Brandan Wustefeld-Janssens, Karen Park, Janet A. Grimes, Michelle Oblak, Carolyn Chen, Sue Casale, Amanda Rollins, Katie Kennedy, Jordan Wilson, William T.N. Culp, Vincent A. Wavreille

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE To provide information about complication rates and the risk factors for complications with mandibulectomy and maxillectomy procedures in dogs. ANIMALS 459 client-owned dogs that underwent a mandibulectomy or maxillectomy between January 1, 2007, and January 1, 2018. PROCEDURES Inclusion criteria included a complete medical record that contained an anesthesia record, surgical report, available histopathology results, and results of CBC and serum biochemical analysis before surgery. A minimum follow-up of 90 days after surgery was required. RESULTS 271 complications occurred in 171 of 459 (37.3%) dogs. Eighteen complications were not given a severity description. Of the remaining 253 complications, most were considered minor (157/253 [62.1%]). Multivariable logistic regression analysis revealed that only increased surgical time had a significant (OR, 1.36; 95% CI, 1.12 to 1.54) association with the occurrence of ≥ 1 complication. For each additional hour of surgery, the odds of complications increased by 36%. Preoperative radiation therapy or chemotherapy increased the odds of incisional dehiscence or oral fistula formation (OR, 3.0; 95% CI, 1.3 to 7.2). Additionally, undergoing maxillectomy, compared with mandibulectomy, increased the odds of incisional dehiscence or oral fistula formation (OR, 1.8; 95% CI, 1.1 to 3.1). Two hundred forty-four of 271 (90.0%) complications occurred in the perioperative period (0 to 3 months after surgery). CONCLUSIONS AND CLINICAL RELEVANCE Compared with mandibulectomy, performing maxillectomy increased the risk for incisional dehiscence or oral fistula formation. Mandibulectomy and maxillectomy had a moderate risk for a complication.

Original languageEnglish (US)
Pages (from-to)265-274
Number of pages10
JournalJournal of the American Veterinary Medical Association
Volume259
Issue number3
DOIs
StatePublished - Aug 1 2021

ASJC Scopus subject areas

  • veterinary(all)

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