Analysis of gene expression during development: lessons from the Apicomplexa

Jon P. Boyle, Jeroen Saeij, Michael D. Cleary, John C. Boothroyd

Research output: Contribution to journalShort survey

16 Scopus citations

Abstract

Apicomplexans are responsible for significant human and animal disease worldwide, including malaria and toxoplasmosis. Herein we summarize recent advances in gene expression analysis in these eukaryotic pathogens, especially with respect to their developmental biology, and discuss the impact this work may have on the development of new vaccines and chemotherapeutics.

Original languageEnglish (US)
Pages (from-to)1623-1630
Number of pages8
JournalMicrobes and Infection
Volume8
Issue number6
DOIs
StatePublished - May 2006
Externally publishedYes

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Keywords

  • Histone deacetylases
  • Host-parasite relationship
  • Malaria
  • Microarray analysis
  • Toxoplasmosis

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

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