An outbreak of yersinia enterocolitica in a captive colony of african green monkeys (Chlorocebus aethiops sabaeus) in the Caribbean

Esteban Soto Martinez, Matt Griffin, Ashutosh Verma, Fernanda Castillo-Alcala, Amy Beierschmitt, Janet Beeler-Marfisi, Maziel Arauz, Oscar Illanes

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Yersinia enterocolitica is a zoonotic gram-negative pathogen that causes mesenteric lymphadenitis, terminal ileitis, acute gastroenteritis, and septicemia in domestic animals and primates. In 2012, 46 captive African green monkeys (Chlorocebus aethiops sabaeus) died during an outbreak of acutely fatal enteric disease over a period of 1 mo on the island of St Kitts. The affected monkeys presented with a history of mucohemorrhagic diarrhea, marked dehydration, and depression. Fifteen bacterial isolates were recovered from the spleen, liver, and lungs of affected monkeys. All isolates were identified as Y. enterocolitica by biochemical analysis and sequence comparison of the 16S rRNA gene. Phenotypic and genotypic analysis of the recovered isolates revealed homogeneity among the recovered bacteria, and all isolates gave a random amplified polymorphic DNA pattern resembling that given by genotype D under serotypes O:7,8. This outbreak represents the first isolation and characterization of Y. enterocolitica as the causative agent of fatal enteric disease in primates in the Caribbean.

Original languageEnglish (US)
Pages (from-to)439-444
Number of pages6
JournalComparative Medicine
Volume63
Issue number5
StatePublished - Oct 2013
Externally publishedYes

Fingerprint

Cercopithecus aethiops
Yersinia enterocolitica
Disease Outbreaks
digestive system diseases
Primate Diseases
Haplorhini
monkeys
Mesenteric Lymphadenitis
Primates
Pathogens
Dehydration
Liver
lymphadenitis
random amplified polymorphic DNA technique
Bacteria
Animals
Genes
Domestic Animals
gastroenteritis
Zoonoses

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)

Cite this

Soto Martinez, E., Griffin, M., Verma, A., Castillo-Alcala, F., Beierschmitt, A., Beeler-Marfisi, J., ... Illanes, O. (2013). An outbreak of yersinia enterocolitica in a captive colony of african green monkeys (Chlorocebus aethiops sabaeus) in the Caribbean. Comparative Medicine, 63(5), 439-444.

An outbreak of yersinia enterocolitica in a captive colony of african green monkeys (Chlorocebus aethiops sabaeus) in the Caribbean. / Soto Martinez, Esteban; Griffin, Matt; Verma, Ashutosh; Castillo-Alcala, Fernanda; Beierschmitt, Amy; Beeler-Marfisi, Janet; Arauz, Maziel; Illanes, Oscar.

In: Comparative Medicine, Vol. 63, No. 5, 10.2013, p. 439-444.

Research output: Contribution to journalArticle

Soto Martinez, E, Griffin, M, Verma, A, Castillo-Alcala, F, Beierschmitt, A, Beeler-Marfisi, J, Arauz, M & Illanes, O 2013, 'An outbreak of yersinia enterocolitica in a captive colony of african green monkeys (Chlorocebus aethiops sabaeus) in the Caribbean', Comparative Medicine, vol. 63, no. 5, pp. 439-444.
Soto Martinez, Esteban ; Griffin, Matt ; Verma, Ashutosh ; Castillo-Alcala, Fernanda ; Beierschmitt, Amy ; Beeler-Marfisi, Janet ; Arauz, Maziel ; Illanes, Oscar. / An outbreak of yersinia enterocolitica in a captive colony of african green monkeys (Chlorocebus aethiops sabaeus) in the Caribbean. In: Comparative Medicine. 2013 ; Vol. 63, No. 5. pp. 439-444.
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