An outbreak of rubella in the Federation of Bosnia and Herzegovina between December 2009 and May 2010 indicates failure to vaccinate during wartime (1992-1995)

M. Hukic, J. M. Hübschen, M. Seremet, I. Salimovic-Besic, M. Mulaomerovic, N. Mehinovic, Siddika E Karakas, E. Charpentier, C. P. Muller

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6 Scopus citations


A rubella outbreak involving 1900 cases was recorded in the Federation of Bosnia and Herzegovina between mid-December 2009 and the end of May 2010. Sera from 389 suspected rubella cases were examined for the presence of rubella-specific IgM and IgG antibodies. A total of 32 throat swabs from suspected rubella cases were tested by RT-PCR and were used to attempt virus isolation. Most patients (945/1900, 49·73%) had never received rubella vaccination or had an unknown vaccination status (563/1900, 29·63%). About 45% (178/389) of suspected rubella patients were IgM positive. From 13 of the throat swabs a virus isolate and E1 gene sequences attributed to genotype 2B were obtained. The rubella outbreak was due to failure to vaccinate during the war period (1992-1995) and emphasizes the need for additional vaccination opportunities.

Original languageEnglish (US)
Pages (from-to)447-453
Number of pages7
JournalEpidemiology and Infection
Issue number3
StatePublished - Mar 1 2012
Externally publishedYes



  • Bosnia and Herzegovina
  • genotype
  • outbreak
  • rubella
  • vaccination

ASJC Scopus subject areas

  • Infectious Diseases
  • Epidemiology

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