Abstract
Bovine viral diarrhea virus 1 (BVDV-1) subtype b was isolated from premature Holstein calves from a dairy herd that experienced an outbreak of premature births, late-term abortions, brachygnathism, growth retardation, malformations of the brain and cranium, and rare extracranial skeletal malformations in calves born to first-calf heifers. Experimental inoculation of 3 colostrum-deprived calves aged 2-4 months old with this BVDV isolate resulted in thrombocytopenia, lymphopenia, and leukopenia. Outbreaks of brachygnathism are rarely associated with BVDV, and thrombocytopenia is rarely associated with BVDV-1 strains.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 128-131 |
| Number of pages | 4 |
| Journal | Journal of Veterinary Diagnostic Investigation |
| Volume | 22 |
| Issue number | 1 |
| State | Published - Jan 1 2010 |
Keywords
- Bovine viral diarrhea virus
- Brachygnathism
- Congenital defects
- Thrombocytopenia
ASJC Scopus subject areas
- veterinary(all)
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Blanchard, P. C., Ridpath, J. F., Walker, J. B., & Hietala, S. K. (2010). An outbreak of late-term abortions, premature births, and congenital deformities associated with a bovine viral diarrhea virus 1 subtype b that induces thrombocytopenia. Journal of Veterinary Diagnostic Investigation, 22(1), 128-131.