An outbreak of late-term abortions, premature births, and congenital deformities associated with a bovine viral diarrhea virus 1 subtype b that induces thrombocytopenia

Patricia C Blanchard, Julia F. Ridpath, Jennifer B. Walker, Sharon K. Hietala

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Bovine viral diarrhea virus 1 (BVDV-1) subtype b was isolated from premature Holstein calves from a dairy herd that experienced an outbreak of premature births, late-term abortions, brachygnathism, growth retardation, malformations of the brain and cranium, and rare extracranial skeletal malformations in calves born to first-calf heifers. Experimental inoculation of 3 colostrum-deprived calves aged 2-4 months old with this BVDV isolate resulted in thrombocytopenia, lymphopenia, and leukopenia. Outbreaks of brachygnathism are rarely associated with BVDV, and thrombocytopenia is rarely associated with BVDV-1 strains.

Original languageEnglish (US)
Pages (from-to)128-131
Number of pages4
JournalJournal of Veterinary Diagnostic Investigation
Volume22
Issue number1
StatePublished - Jan 1 2010

Keywords

  • Bovine viral diarrhea virus
  • Brachygnathism
  • Congenital defects
  • Thrombocytopenia

ASJC Scopus subject areas

  • veterinary(all)

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