An M. tuberculosis Metabolic Enzyme Moonlights as an Anti-Inflammatory Effector Protein

Tina Truong; Bennett H. Penn

doi:10.1016/j.chom.2020.02.012

An M. tuberculosis Metabolic Enzyme Moonlights as an Anti-Inflammatory Effector Protein

Tina Truong, Bennett H. Penn

Infectious Diseases, Medical Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The mechanisms by which Mycobacterium tuberculosis evades host immunity remain enigmatic. In a recent study in the journal Nature, Wang et al. report that an enzyme acting in the bacterial cytoplasm to degrade lipids also acts as an effector protein in the host cell cytoplasm to suppress inflammation.

Original language	English (US)
Pages (from-to)	310-312
Number of pages	3
Journal	Cell Host and Microbe
Volume	27
Issue number	3
DOIs	https://doi.org/10.1016/j.chom.2020.02.012
State	Published - Mar 11 2020

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

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abstract = "The mechanisms by which Mycobacterium tuberculosis evades host immunity remain enigmatic. In a recent study in the journal Nature, Wang et al. report that an enzyme acting in the bacterial cytoplasm to degrade lipids also acts as an effector protein in the host cell cytoplasm to suppress inflammation.",

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