Abstract
An intramolecular 1,3-dipolar cycloaddition/ electrophilic cyclization sequence has been developed for the synthesis of cyclic ethers. This approach utilizes a diastereoselective nitrile oxide 1,3-dipolar cycloaddition to give furoisoxazoles, which undergo subsequent electrophilic cyclization to afford substituted tetrahydrofurans.
Original language | English (US) |
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Pages (from-to) | 7320-7321 |
Number of pages | 2 |
Journal | Journal of Organic Chemistry |
Volume | 58 |
Issue number | 26 |
State | Published - 1993 |
ASJC Scopus subject areas
- Organic Chemistry