An in vitro study on spontaneous myometrial contractility in the cow during estrus and diestrus

Gaby Hirsbrunner, B. Knutti, Irwin Liu, U. Küpfer, G. Scholtysik, A. Steiner

Research output: Contribution to journalArticle

26 Scopus citations


Myometrial smooth muscle strips were collected from slaughtered cows in estrus and diestrus. Longitudinal and circular smooth muscle strips were mounted in organ baths and after equilibration time and 2 g preload, their physiologic contractility was recorded for 3 h. Area under the curve (AUC), mean amplitude (MA) and frequency of contractions (F) were studied. Differences between cycle phases, between muscle layers and over the recorded time period were statistically evaluated. In the cow, physiologic contractility patterns (measured as AUC and MA) of circular versus longitudinal myometrial strips are always different during the 3 h recording. Significant differences between estrus versus diestrus are only found for circular layers, but not for longitudinal layers. Significant differences over time are only found for longitudinal layers.

Original languageEnglish (US)
Pages (from-to)171-180
Number of pages10
JournalAnimal Reproduction Science
Issue number3-4
StatePublished - Apr 15 2002
Externally publishedYes



  • Cattle
  • Cycle phase
  • Myometrium
  • Organ bath
  • Physiology
  • Uterus

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology
  • Endocrinology

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