TY - JOUR
T1 - An immunohistochemical study of the endocrine pancreas in raptors
AU - Palmieri, C.
AU - Shivaprasad, H L
PY - 2014/12/1
Y1 - 2014/12/1
N2 - The cytoarchitecture of the endocrine pancreas of 10 raptors (golden eagles, peregrine falcons, Saker falcon, turkey vultures, red-tailed hawk and unspecified falcon) was examined by immunohistochemistry. Three islet types were identified: type A mixed islets composed mainly by glucagon (A)-secreting cells, type B mixed islets with predominantly insulin (B)-secreting cell component and type M mixed islets (type M) consisting of variable number of glucagon-, insulin- and somatostatin (D)-secreting cells. The latter were further characterized into Type I, II or III according to the cell distribution of the three cell types. A and D cells were also randomly scattered within the exocrine pancreas. The results of this study suggest that the classical concept in birds of a segregation of A and B cells in well-defined and distinct islets is not applicable in raptors, reflecting an evolutionary adaptation to different dietary habits and variation in developmental mechanisms.
AB - The cytoarchitecture of the endocrine pancreas of 10 raptors (golden eagles, peregrine falcons, Saker falcon, turkey vultures, red-tailed hawk and unspecified falcon) was examined by immunohistochemistry. Three islet types were identified: type A mixed islets composed mainly by glucagon (A)-secreting cells, type B mixed islets with predominantly insulin (B)-secreting cell component and type M mixed islets (type M) consisting of variable number of glucagon-, insulin- and somatostatin (D)-secreting cells. The latter were further characterized into Type I, II or III according to the cell distribution of the three cell types. A and D cells were also randomly scattered within the exocrine pancreas. The results of this study suggest that the classical concept in birds of a segregation of A and B cells in well-defined and distinct islets is not applicable in raptors, reflecting an evolutionary adaptation to different dietary habits and variation in developmental mechanisms.
KW - Avian
KW - Endocrine pancreas
KW - Immunohistochemistry
KW - Raptor
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U2 - 10.1016/j.rvsc.2014.10.011
DO - 10.1016/j.rvsc.2014.10.011
M3 - Article
C2 - 25468799
AN - SCOPUS:84918841944
VL - 97
SP - 587
EP - 591
JO - Research in Veterinary Science
JF - Research in Veterinary Science
SN - 0034-5288
IS - 3
ER -