An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus

James A. Kenning; Roberto C. Heros; Manuel Dujovny; Richard E Latchaw; Debra Nelson

doi:10.1016/0090-3019(84)90335-5

An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus

James A. Kenning, Roberto C. Heros, Manuel Dujovny, Richard E Latchaw, Debra Nelson

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The incidence and severity of cerebral vasospasm and hydrocephalus following induced subarachnoid hemorrhage in an experimental group of animals that subsequently received ε-aminocaproic acid was compared to that seen in a control group that received no antifibrinolytic therapy. No augmentation of either vasospasm or hydrocephalus could be attributed to the ε-aminocaproic acid in the treated as compared to the control group.

Original language	English (US)
Pages (from-to)	159-164
Number of pages	6
Journal	Surgical Neurology
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/0090-3019(84)90335-5
State	Published - 1984
Externally published	Yes

Keywords

Aneurysm
Antifibrinolytic therapy
Hydrocephalus
Subarachnoid hemorrhage
Vasospasm
ε-Aminocaproic acid

ASJC Scopus subject areas

Clinical Neurology
Surgery

Access to Document

10.1016/0090-3019(84)90335-5

Fingerprint Dive into the research topics of 'An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus'. Together they form a unique fingerprint.

Cite this

@article{7f6f8127b3bd49a087fcc8cb7e0e6704,

title = "An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus",

abstract = "The incidence and severity of cerebral vasospasm and hydrocephalus following induced subarachnoid hemorrhage in an experimental group of animals that subsequently received ε-aminocaproic acid was compared to that seen in a control group that received no antifibrinolytic therapy. No augmentation of either vasospasm or hydrocephalus could be attributed to the ε-aminocaproic acid in the treated as compared to the control group.",

keywords = "Aneurysm, Antifibrinolytic therapy, Hydrocephalus, Subarachnoid hemorrhage, Vasospasm, ε-Aminocaproic acid",

author = "Kenning, {James A.} and Heros, {Roberto C.} and Manuel Dujovny and Latchaw, {Richard E} and Debra Nelson",

year = "1984",

doi = "10.1016/0090-3019(84)90335-5",

language = "English (US)",

volume = "21",

pages = "159--164",

journal = "World Neurosurgery",

issn = "1878-8750",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - An experimental study of the influence of antifibrinolytic therapy on post-subarachnoid-hemorrhagic cerebral vasospasm and hydrocephalus

AU - Kenning, James A.

AU - Heros, Roberto C.

AU - Dujovny, Manuel

AU - Latchaw, Richard E

AU - Nelson, Debra

PY - 1984

Y1 - 1984

N2 - The incidence and severity of cerebral vasospasm and hydrocephalus following induced subarachnoid hemorrhage in an experimental group of animals that subsequently received ε-aminocaproic acid was compared to that seen in a control group that received no antifibrinolytic therapy. No augmentation of either vasospasm or hydrocephalus could be attributed to the ε-aminocaproic acid in the treated as compared to the control group.

AB - The incidence and severity of cerebral vasospasm and hydrocephalus following induced subarachnoid hemorrhage in an experimental group of animals that subsequently received ε-aminocaproic acid was compared to that seen in a control group that received no antifibrinolytic therapy. No augmentation of either vasospasm or hydrocephalus could be attributed to the ε-aminocaproic acid in the treated as compared to the control group.

KW - Aneurysm

KW - Antifibrinolytic therapy

KW - Hydrocephalus

KW - Subarachnoid hemorrhage

KW - Vasospasm

KW - ε-Aminocaproic acid

UR - http://www.scopus.com/inward/record.url?scp=0021331755&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021331755&partnerID=8YFLogxK

U2 - 10.1016/0090-3019(84)90335-5

DO - 10.1016/0090-3019(84)90335-5

M3 - Article

C2 - 6701753

AN - SCOPUS:0021331755

VL - 21

SP - 159

EP - 164

JO - World Neurosurgery

JF - World Neurosurgery

SN - 1878-8750

IS - 2

ER -