Abstract
An ellipsometry-based biosensor, the oblique-incidence reflectivity difference (OI-RD) scanning microscope, was developed for label-free, real-time, and in-situ detection of biomolecular interactions. We successfully demonstrate that DNA-DNA hybridization and DNA-protein reactions in a DNA microarray can be monitored by such an OI-RD microscope.
Original language | English (US) |
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Pages (from-to) | 1398-1406 |
Number of pages | 9 |
Journal | Chinese Journal of Physics |
Volume | 52 |
Issue number | 4 |
DOIs | |
State | Published - 2014 |
ASJC Scopus subject areas
- Physics and Astronomy(all)