Abstract
An ellipsometry-based biosensor, the oblique-incidence reflectivity difference (OI-RD) scanning microscope, was developed for label-free, real-time, and in-situ detection of biomolecular interactions. We successfully demonstrate that DNA-DNA hybridization and DNA-protein reactions in a DNA microarray can be monitored by such an OI-RD microscope.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1398-1406 |
| Number of pages | 9 |
| Journal | Chinese Journal of Physics |
| Volume | 52 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2014 |
ASJC Scopus subject areas
- Physics and Astronomy(all)