An adult case of acute lymphoblastic leukaemia presenting as hepatic dysfunction

C. A. Aoki; Christopher Bowlus; Lorenzo Rossaro

doi:10.1016/j.dld.2004.05.016

An adult case of acute lymphoblastic leukaemia presenting as hepatic dysfunction

C. A. Aoki, Christopher Bowlus, Lorenzo Rossaro

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Acute hepatic dysfunction is a rare and often fatal presentation of haematological malignancies. We describe an adult case of acute lymphoblastic leukaemia presenting as an acute hepatitis. Due to the elevation in the patient's transaminases and bilirubin, standard acute lymphoblastic leukaemia induction therapy could not be used. Instead the combination of prednisone and asaparaginase were used to successfully induce remission.

Original language	English (US)
Pages (from-to)	206-210
Number of pages	5
Journal	Digestive and Liver Disease
Volume	37
Issue number	3
DOIs	https://doi.org/10.1016/j.dld.2004.05.016
State	Published - Mar 2005

Keywords

Asaparaginase
Hepatic dysfunction
Hepatitis
Leukaemia
Prednisone

ASJC Scopus subject areas

Gastroenterology

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10.1016/j.dld.2004.05.016

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title = "An adult case of acute lymphoblastic leukaemia presenting as hepatic dysfunction",

abstract = "Acute hepatic dysfunction is a rare and often fatal presentation of haematological malignancies. We describe an adult case of acute lymphoblastic leukaemia presenting as an acute hepatitis. Due to the elevation in the patient's transaminases and bilirubin, standard acute lymphoblastic leukaemia induction therapy could not be used. Instead the combination of prednisone and asaparaginase were used to successfully induce remission.",

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author = "Aoki, {C. A.} and Christopher Bowlus and Lorenzo Rossaro",

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AU - Bowlus, Christopher

AU - Rossaro, Lorenzo

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N2 - Acute hepatic dysfunction is a rare and often fatal presentation of haematological malignancies. We describe an adult case of acute lymphoblastic leukaemia presenting as an acute hepatitis. Due to the elevation in the patient's transaminases and bilirubin, standard acute lymphoblastic leukaemia induction therapy could not be used. Instead the combination of prednisone and asaparaginase were used to successfully induce remission.

AB - Acute hepatic dysfunction is a rare and often fatal presentation of haematological malignancies. We describe an adult case of acute lymphoblastic leukaemia presenting as an acute hepatitis. Due to the elevation in the patient's transaminases and bilirubin, standard acute lymphoblastic leukaemia induction therapy could not be used. Instead the combination of prednisone and asaparaginase were used to successfully induce remission.

KW - Asaparaginase

KW - Hepatic dysfunction

KW - Hepatitis

KW - Leukaemia

KW - Prednisone

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ER -

An adult case of acute lymphoblastic leukaemia presenting as hepatic dysfunction

Abstract

Keywords

ASJC Scopus subject areas

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