TY - JOUR
T1 - Amphotericin B-impregnated bone cement to treat refractory coccidioidal osteomyelitis
AU - Zhu, Elizabeth S.
AU - Thompson, George Richard
AU - Kreulen, Christopher
AU - Giza, Eric
PY - 2013/12
Y1 - 2013/12
N2 - Use of amphotericin B-impregnated bone cement in combination with systemic antifungals for the treatment of coccidioidal osteomyelitis offers the potential for sustained local concentrations of drug at the site of the infection. Amphotericin B levels in bone of up to 5.1 μg/g have been demonstrated 4 months after placement of bone cement.
AB - Use of amphotericin B-impregnated bone cement in combination with systemic antifungals for the treatment of coccidioidal osteomyelitis offers the potential for sustained local concentrations of drug at the site of the infection. Amphotericin B levels in bone of up to 5.1 μg/g have been demonstrated 4 months after placement of bone cement.
UR - http://www.scopus.com/inward/record.url?scp=84887415170&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887415170&partnerID=8YFLogxK
U2 - 10.1128/AAC.00963-13
DO - 10.1128/AAC.00963-13
M3 - Article
C2 - 24002101
AN - SCOPUS:84887415170
VL - 57
SP - 6341
EP - 6343
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 12
ER -