Abstract
Post-trial injections of norepinephrine (NE) or cycloheximide (CHX) into the amygdala produces a long-term retention deficit (amnesia) for a 1-trial footshock experience in rats. Concomitant post-trial injections of the adrenergic antagonist, propranolol, prevents NE-, but not CHX-induced amnesia. These results indicate separate mechanisms of action for amnesia produced by intracranial CHX and NE injections.
Original language | English (US) |
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Pages (from-to) | 733-736 |
Number of pages | 4 |
Journal | Pharmacology, Biochemistry and Behavior |
Volume | 19 |
Issue number | 5 |
DOIs | |
State | Published - 1983 |
Externally published | Yes |
Keywords
- Amnesia
- Amygdala
- Aversive information processing
- Cycloheximide
- Differential attenuation
- Memory mechanisms
- Norepinephrine
- Propranolol
ASJC Scopus subject areas
- Biochemistry
- Behavioral Neuroscience
- Pharmacology