Ammonia intoxication in the near-adult cat as a result of a dietary deficiency of arginine

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Abstract

Near-adult cats, fasted overnight, and given a single meal ofa complete amino acid diet without arginine, developed hyperammonemia and showed clinical symptoms of ammonia toxicity within 2 hours. One cat (2.7 kilograms) died 4.5 hours after ingesting only 8 grams of the diet. Since ornithine also prevented hyperammonemia, it appears that the domestic cat cannot synthesize ornithine.

Original languageEnglish (US)
Pages (from-to)431-432
Number of pages2
JournalScience
Volume199
Issue number4327
DOIs
StatePublished - Jan 1 1978

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