Abstract
Amelogenins are major enamel proteins within the enamel extracellular matrix. The expression of amelogenin was confirmed in neonatal tissues of the canine jaw. The sequence of a portion of canine amelogenin cDNA, within exons 5 and 6, was determined and found to be closely homologous to sequences reported in the cow, pig, mouse and human being. Two acanthomatous epulides collected from clinically affected dogs showed amelogenin expression, whereas 22 other canine oral lesions, including six additional acanthomatous epulides, did not show amelogenin expression. Examination of structural proteins may allow precise identification of the histogenesis of the odontogenic neoplasms, which are often difficult to distinguish by means of morphological criteria alone.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 15-25 |
| Number of pages | 11 |
| Journal | Journal of Comparative Pathology |
| Volume | 119 |
| Issue number | 1 |
| State | Published - 1998 |
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ASJC Scopus subject areas
- Animal Science and Zoology
Cite this
Amelogenin expression in canine oral tissues and lesions. / Yuasa, Y.; Kraegel, S. A.; Verstraete, Frank J; Winthrop, M.; Griffey, Stephen M; Madewell, B. R.
In: Journal of Comparative Pathology, Vol. 119, No. 1, 1998, p. 15-25.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Amelogenin expression in canine oral tissues and lesions
AU - Yuasa, Y.
AU - Kraegel, S. A.
AU - Verstraete, Frank J
AU - Winthrop, M.
AU - Griffey, Stephen M
AU - Madewell, B. R.
PY - 1998
Y1 - 1998
N2 - Amelogenins are major enamel proteins within the enamel extracellular matrix. The expression of amelogenin was confirmed in neonatal tissues of the canine jaw. The sequence of a portion of canine amelogenin cDNA, within exons 5 and 6, was determined and found to be closely homologous to sequences reported in the cow, pig, mouse and human being. Two acanthomatous epulides collected from clinically affected dogs showed amelogenin expression, whereas 22 other canine oral lesions, including six additional acanthomatous epulides, did not show amelogenin expression. Examination of structural proteins may allow precise identification of the histogenesis of the odontogenic neoplasms, which are often difficult to distinguish by means of morphological criteria alone.
AB - Amelogenins are major enamel proteins within the enamel extracellular matrix. The expression of amelogenin was confirmed in neonatal tissues of the canine jaw. The sequence of a portion of canine amelogenin cDNA, within exons 5 and 6, was determined and found to be closely homologous to sequences reported in the cow, pig, mouse and human being. Two acanthomatous epulides collected from clinically affected dogs showed amelogenin expression, whereas 22 other canine oral lesions, including six additional acanthomatous epulides, did not show amelogenin expression. Examination of structural proteins may allow precise identification of the histogenesis of the odontogenic neoplasms, which are often difficult to distinguish by means of morphological criteria alone.
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UR - http://www.scopus.com/inward/citedby.url?scp=0031857147&partnerID=8YFLogxK
M3 - Article
C2 - 9717124
AN - SCOPUS:0031857147
VL - 119
SP - 15
EP - 25
JO - Journal of Comparative Pathology
JF - Journal of Comparative Pathology
SN - 0021-9975
IS - 1
ER -