Amelogenin expression in canine oral tissues and lesions

Y. Yuasa, S. A. Kraegel, Frank J Verstraete, M. Winthrop, Stephen M Griffey, B. R. Madewell

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Amelogenins are major enamel proteins within the enamel extracellular matrix. The expression of amelogenin was confirmed in neonatal tissues of the canine jaw. The sequence of a portion of canine amelogenin cDNA, within exons 5 and 6, was determined and found to be closely homologous to sequences reported in the cow, pig, mouse and human being. Two acanthomatous epulides collected from clinically affected dogs showed amelogenin expression, whereas 22 other canine oral lesions, including six additional acanthomatous epulides, did not show amelogenin expression. Examination of structural proteins may allow precise identification of the histogenesis of the odontogenic neoplasms, which are often difficult to distinguish by means of morphological criteria alone.

Original languageEnglish (US)
Pages (from-to)15-25
Number of pages11
JournalJournal of Comparative Pathology
Volume119
Issue number1
StatePublished - 1998

Fingerprint

Amelogenin
lesions (animal)
Canidae
mouth
Gingival Diseases
dogs
enamel
Dental Enamel
structural proteins
jaws
extracellular matrix
morphogenesis
exons
Sequence Homology
Jaw
Extracellular Matrix
Exons
Proteins
cows
Swine

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Yuasa, Y., Kraegel, S. A., Verstraete, F. J., Winthrop, M., Griffey, S. M., & Madewell, B. R. (1998). Amelogenin expression in canine oral tissues and lesions. Journal of Comparative Pathology, 119(1), 15-25.

Amelogenin expression in canine oral tissues and lesions. / Yuasa, Y.; Kraegel, S. A.; Verstraete, Frank J; Winthrop, M.; Griffey, Stephen M; Madewell, B. R.

In: Journal of Comparative Pathology, Vol. 119, No. 1, 1998, p. 15-25.

Research output: Contribution to journalArticle

Yuasa, Y, Kraegel, SA, Verstraete, FJ, Winthrop, M, Griffey, SM & Madewell, BR 1998, 'Amelogenin expression in canine oral tissues and lesions', Journal of Comparative Pathology, vol. 119, no. 1, pp. 15-25.
Yuasa, Y. ; Kraegel, S. A. ; Verstraete, Frank J ; Winthrop, M. ; Griffey, Stephen M ; Madewell, B. R. / Amelogenin expression in canine oral tissues and lesions. In: Journal of Comparative Pathology. 1998 ; Vol. 119, No. 1. pp. 15-25.
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