Ameloblastic carcinoma in a horse

H. E V De Cock, P. Labelle, K G Magdesian

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


The clinical, gross morphological, histological and immunohistochemical characteristics of an ameloblastic carcinoma in a 30-year-old Quarter Horse mare are reported. This tumour was fast growing, locally invasive and destructive. Histologically, it showed an infiltrative pattern of large islands, broad sheets and, at the periphery, small cords of moderately pleomorphic round, oval to spindle-shaped cells. Immunohistochemical evaluation revealed positive labelling for vimentin, cytokeratin 5/6 and cytokeratin 14. In the oral cavity of human beings, this immunolabelling pattern is unique for the embryonal enamel organ and tumours of ameloblastomatous epithelial origin, which strongly supports the diagnosis of equine ameloblastic carcinoma.

Original languageEnglish (US)
Pages (from-to)210-215
Number of pages6
JournalJournal of Comparative Pathology
Issue number2-3
StatePublished - Feb 2003

ASJC Scopus subject areas

  • Animal Science and Zoology


Dive into the research topics of 'Ameloblastic carcinoma in a horse'. Together they form a unique fingerprint.

Cite this