Ameloblastic carcinoma in a horse

H. E V De Cock; P. Labelle; K G Magdesian

doi:10.1053/jcpa.2002.0623

Ameloblastic carcinoma in a horse

H. E V De Cock, P. Labelle, K G Magdesian

Medicine and Epidemiology

Research output: Contribution to journal › Article

15 Scopus citations

Abstract

The clinical, gross morphological, histological and immunohistochemical characteristics of an ameloblastic carcinoma in a 30-year-old Quarter Horse mare are reported. This tumour was fast growing, locally invasive and destructive. Histologically, it showed an infiltrative pattern of large islands, broad sheets and, at the periphery, small cords of moderately pleomorphic round, oval to spindle-shaped cells. Immunohistochemical evaluation revealed positive labelling for vimentin, cytokeratin 5/6 and cytokeratin 14. In the oral cavity of human beings, this immunolabelling pattern is unique for the embryonal enamel organ and tumours of ameloblastomatous epithelial origin, which strongly supports the diagnosis of equine ameloblastic carcinoma.

Original language	English (US)
Pages (from-to)	210-215
Number of pages	6
Journal	Journal of Comparative Pathology
Volume	128
Issue number	2-3
DOIs	https://doi.org/10.1053/jcpa.2002.0623
State	Published - Feb 2003

Fingerprint

ASJC Scopus subject areas

Animal Science and Zoology

Cite this

De Cock, H. E. V., Labelle, P., & Magdesian, K. G. (2003). Ameloblastic carcinoma in a horse. Journal of Comparative Pathology, 128(2-3), 210-215. https://doi.org/10.1053/jcpa.2002.0623

@article{881b38200e174a97a831b0a1503db022,

title = "Ameloblastic carcinoma in a horse",

abstract = "The clinical, gross morphological, histological and immunohistochemical characteristics of an ameloblastic carcinoma in a 30-year-old Quarter Horse mare are reported. This tumour was fast growing, locally invasive and destructive. Histologically, it showed an infiltrative pattern of large islands, broad sheets and, at the periphery, small cords of moderately pleomorphic round, oval to spindle-shaped cells. Immunohistochemical evaluation revealed positive labelling for vimentin, cytokeratin 5/6 and cytokeratin 14. In the oral cavity of human beings, this immunolabelling pattern is unique for the embryonal enamel organ and tumours of ameloblastomatous epithelial origin, which strongly supports the diagnosis of equine ameloblastic carcinoma.",

author = "{De Cock}, {H. E V} and P. Labelle and Magdesian, {K G}",

year = "2003",

month = feb

doi = "10.1053/jcpa.2002.0623",

language = "English (US)",

volume = "128",

pages = "210--215",

journal = "Journal of Comparative Pathology",

issn = "0021-9975",

publisher = "W.B. Saunders Ltd",

number = "2-3",

}

TY - JOUR

T1 - Ameloblastic carcinoma in a horse

AU - De Cock, H. E V

AU - Labelle, P.

AU - Magdesian, K G

PY - 2003/2

Y1 - 2003/2

N2 - The clinical, gross morphological, histological and immunohistochemical characteristics of an ameloblastic carcinoma in a 30-year-old Quarter Horse mare are reported. This tumour was fast growing, locally invasive and destructive. Histologically, it showed an infiltrative pattern of large islands, broad sheets and, at the periphery, small cords of moderately pleomorphic round, oval to spindle-shaped cells. Immunohistochemical evaluation revealed positive labelling for vimentin, cytokeratin 5/6 and cytokeratin 14. In the oral cavity of human beings, this immunolabelling pattern is unique for the embryonal enamel organ and tumours of ameloblastomatous epithelial origin, which strongly supports the diagnosis of equine ameloblastic carcinoma.

AB - The clinical, gross morphological, histological and immunohistochemical characteristics of an ameloblastic carcinoma in a 30-year-old Quarter Horse mare are reported. This tumour was fast growing, locally invasive and destructive. Histologically, it showed an infiltrative pattern of large islands, broad sheets and, at the periphery, small cords of moderately pleomorphic round, oval to spindle-shaped cells. Immunohistochemical evaluation revealed positive labelling for vimentin, cytokeratin 5/6 and cytokeratin 14. In the oral cavity of human beings, this immunolabelling pattern is unique for the embryonal enamel organ and tumours of ameloblastomatous epithelial origin, which strongly supports the diagnosis of equine ameloblastic carcinoma.

UR - http://www.scopus.com/inward/record.url?scp=0037330140&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037330140&partnerID=8YFLogxK

U2 - 10.1053/jcpa.2002.0623

DO - 10.1053/jcpa.2002.0623

M3 - Article

C2 - 12634103

AN - SCOPUS:0037330140

VL - 128

SP - 210

EP - 215

JO - Journal of Comparative Pathology

JF - Journal of Comparative Pathology

SN - 0021-9975

IS - 2-3

ER -

Access to Document

10.1053/jcpa.2002.0623