Ameloblastic carcinoma in a horse

H. E V De Cock, P. Labelle, K G Magdesian

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The clinical, gross morphological, histological and immunohistochemical characteristics of an ameloblastic carcinoma in a 30-year-old Quarter Horse mare are reported. This tumour was fast growing, locally invasive and destructive. Histologically, it showed an infiltrative pattern of large islands, broad sheets and, at the periphery, small cords of moderately pleomorphic round, oval to spindle-shaped cells. Immunohistochemical evaluation revealed positive labelling for vimentin, cytokeratin 5/6 and cytokeratin 14. In the oral cavity of human beings, this immunolabelling pattern is unique for the embryonal enamel organ and tumours of ameloblastomatous epithelial origin, which strongly supports the diagnosis of equine ameloblastic carcinoma.

Original languageEnglish (US)
Pages (from-to)210-215
Number of pages6
JournalJournal of Comparative Pathology
Volume128
Issue number2-3
DOIs
StatePublished - Feb 2003

Fingerprint

Horses
carcinoma
Enamel Organ
Keratin-6
Keratin-14
Keratin-5
Carcinoma
horses
Quarter Horse
neoplasms
enamel
vimentin
Vimentin
Islands
mares
Mouth
mouth
Neoplasms
cells

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Ameloblastic carcinoma in a horse. / De Cock, H. E V; Labelle, P.; Magdesian, K G.

In: Journal of Comparative Pathology, Vol. 128, No. 2-3, 02.2003, p. 210-215.

Research output: Contribution to journalArticle

De Cock, H. E V ; Labelle, P. ; Magdesian, K G. / Ameloblastic carcinoma in a horse. In: Journal of Comparative Pathology. 2003 ; Vol. 128, No. 2-3. pp. 210-215.
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