Ambulatory treatment of suspected pelvic inflammatory disease with Augmentin, with or without doxycycline

Pål Wølner-Hanssen, Jorma Paavonen, Nancy Kiviat, Daniel Landers, Richard L Sweet, David A. Eschenbach, King K. Holmes

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Sixty-three women with suspected pelvic inflammatory disease were treated as outpatients with Augmentin with or without doxycycline. Initially, doxycycline was added only after a direct immunofluorescence test for Chlamydia trachomatis was positive. Because chlamydial infections were frequent, all patients received doxycycline during the last two thirds of the study. Neisseria gonorrhoeae or Chlamydia trachomatis were recovered from 15 (65%) of 23 women classified as probably having pelvic inflammatory disease. Among 47 women reexamined after starting therapy, three rapidly became worse and were hospitalized, nine (20%) discontinued therapy because of gastrointestinal side effects, and all of the remaining 35 women who completed therapy were either cured or improved.

Original languageEnglish (US)
Pages (from-to)577-579
Number of pages3
JournalAmerican Journal of Obstetrics and Gynecology
Volume158
Issue number3 PART 1
DOIs
StatePublished - 1988

Fingerprint

Amoxicillin-Potassium Clavulanate Combination
Pelvic Inflammatory Disease
Doxycycline
Chlamydia trachomatis
Direct Fluorescent Antibody Technique
Neisseria gonorrhoeae
Therapeutics
Outpatients
Infection

Keywords

  • Augmentin
  • Chlamydia trachomatis
  • doxycycline
  • Neisseria gonorrhoeae
  • treatment of pelvic inflammatory disease

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Ambulatory treatment of suspected pelvic inflammatory disease with Augmentin, with or without doxycycline. / Wølner-Hanssen, Pål; Paavonen, Jorma; Kiviat, Nancy; Landers, Daniel; Sweet, Richard L; Eschenbach, David A.; Holmes, King K.

In: American Journal of Obstetrics and Gynecology, Vol. 158, No. 3 PART 1, 1988, p. 577-579.

Research output: Contribution to journalArticle

Wølner-Hanssen, Pål ; Paavonen, Jorma ; Kiviat, Nancy ; Landers, Daniel ; Sweet, Richard L ; Eschenbach, David A. ; Holmes, King K. / Ambulatory treatment of suspected pelvic inflammatory disease with Augmentin, with or without doxycycline. In: American Journal of Obstetrics and Gynecology. 1988 ; Vol. 158, No. 3 PART 1. pp. 577-579.
@article{b6ade7b030e549a2b7cebd7487e4960d,
title = "Ambulatory treatment of suspected pelvic inflammatory disease with Augmentin, with or without doxycycline",
abstract = "Sixty-three women with suspected pelvic inflammatory disease were treated as outpatients with Augmentin with or without doxycycline. Initially, doxycycline was added only after a direct immunofluorescence test for Chlamydia trachomatis was positive. Because chlamydial infections were frequent, all patients received doxycycline during the last two thirds of the study. Neisseria gonorrhoeae or Chlamydia trachomatis were recovered from 15 (65{\%}) of 23 women classified as probably having pelvic inflammatory disease. Among 47 women reexamined after starting therapy, three rapidly became worse and were hospitalized, nine (20{\%}) discontinued therapy because of gastrointestinal side effects, and all of the remaining 35 women who completed therapy were either cured or improved.",
keywords = "Augmentin, Chlamydia trachomatis, doxycycline, Neisseria gonorrhoeae, treatment of pelvic inflammatory disease",
author = "P{\aa}l W{\o}lner-Hanssen and Jorma Paavonen and Nancy Kiviat and Daniel Landers and Sweet, {Richard L} and Eschenbach, {David A.} and Holmes, {King K.}",
year = "1988",
doi = "10.1016/0002-9378(88)90030-0",
language = "English (US)",
volume = "158",
pages = "577--579",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "3 PART 1",

}

TY - JOUR

T1 - Ambulatory treatment of suspected pelvic inflammatory disease with Augmentin, with or without doxycycline

AU - Wølner-Hanssen, Pål

AU - Paavonen, Jorma

AU - Kiviat, Nancy

AU - Landers, Daniel

AU - Sweet, Richard L

AU - Eschenbach, David A.

AU - Holmes, King K.

PY - 1988

Y1 - 1988

N2 - Sixty-three women with suspected pelvic inflammatory disease were treated as outpatients with Augmentin with or without doxycycline. Initially, doxycycline was added only after a direct immunofluorescence test for Chlamydia trachomatis was positive. Because chlamydial infections were frequent, all patients received doxycycline during the last two thirds of the study. Neisseria gonorrhoeae or Chlamydia trachomatis were recovered from 15 (65%) of 23 women classified as probably having pelvic inflammatory disease. Among 47 women reexamined after starting therapy, three rapidly became worse and were hospitalized, nine (20%) discontinued therapy because of gastrointestinal side effects, and all of the remaining 35 women who completed therapy were either cured or improved.

AB - Sixty-three women with suspected pelvic inflammatory disease were treated as outpatients with Augmentin with or without doxycycline. Initially, doxycycline was added only after a direct immunofluorescence test for Chlamydia trachomatis was positive. Because chlamydial infections were frequent, all patients received doxycycline during the last two thirds of the study. Neisseria gonorrhoeae or Chlamydia trachomatis were recovered from 15 (65%) of 23 women classified as probably having pelvic inflammatory disease. Among 47 women reexamined after starting therapy, three rapidly became worse and were hospitalized, nine (20%) discontinued therapy because of gastrointestinal side effects, and all of the remaining 35 women who completed therapy were either cured or improved.

KW - Augmentin

KW - Chlamydia trachomatis

KW - doxycycline

KW - Neisseria gonorrhoeae

KW - treatment of pelvic inflammatory disease

UR - http://www.scopus.com/inward/record.url?scp=0023831267&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023831267&partnerID=8YFLogxK

U2 - 10.1016/0002-9378(88)90030-0

DO - 10.1016/0002-9378(88)90030-0

M3 - Article

C2 - 3348319

AN - SCOPUS:0023831267

VL - 158

SP - 577

EP - 579

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 3 PART 1

ER -