Ambulatory treatment of suspected pelvic inflammatory disease with Augmentin, with or without doxycycline

Pål Wølner-Hanssen, Jorma Paavonen, Nancy Kiviat, Daniel Landers, Richard L Sweet, David A. Eschenbach, King K. Holmes

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Sixty-three women with suspected pelvic inflammatory disease were treated as outpatients with Augmentin with or without doxycycline. Initially, doxycycline was added only after a direct immunofluorescence test for Chlamydia trachomatis was positive. Because chlamydial infections were frequent, all patients received doxycycline during the last two thirds of the study. Neisseria gonorrhoeae or Chlamydia trachomatis were recovered from 15 (65%) of 23 women classified as probably having pelvic inflammatory disease. Among 47 women reexamined after starting therapy, three rapidly became worse and were hospitalized, nine (20%) discontinued therapy because of gastrointestinal side effects, and all of the remaining 35 women who completed therapy were either cured or improved.

Original languageEnglish (US)
Pages (from-to)577-579
Number of pages3
JournalAmerican Journal of Obstetrics and Gynecology
Volume158
Issue number3 PART 1
DOIs
StatePublished - 1988

Keywords

  • Augmentin
  • Chlamydia trachomatis
  • doxycycline
  • Neisseria gonorrhoeae
  • treatment of pelvic inflammatory disease

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

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