Amanita phalloides mushroom poisonings - Northern California, December 2016

Kathy T. Vo, Martha E. Montgomery, S. Todd Mitchell, Pieter H. Scheerlinck, Daniel Colby, Kathryn H. Meier, Susan Kim-Katz, Ilene B. Anderson, Steven R. Offerman, Kent R. Olson, Craig G. Smollin

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

What is already known about this topic? Ingestion of Amanita phalloides is responsible for a majority of mushroom-related deaths worldwide. Amatoxins, the principal toxic alkaloids found in these fungi, cause cell injury by halting protein synthesis. A possible antidote licensed in most of Europe, intravenous silibinin, is undergoing evaluation by clinical trial in the United States. What is added by this report? In December 2016, fourteen cases of Amanita phalloides poisoning were identified by the California Poison Control System (CPCS) among persons who had consumed foraged wild mushrooms. In the past few years before this outbreak, CPCS only received reports of a few mushroom poisoning cases per year. All patients in this outbreak had gastrointestinal manifestations of intoxication leading to dehydration and hepatotoxicity. Three patients received liver transplants; all patients recovered, although one (a child) had permanent neurologic impairment. What are the implications for public health practice? Wild-picked mushrooms should be evaluated by a trained mycologist before ingestion. Inexperienced foragers should be strongly discouraged from eating any wild mushrooms. Health care providers should be aware of the potential for toxicity after wild mushroom ingestion, that gastrointestinal symptoms mimicking viral gastroenteritis can occur after ingestion and slowly progress to potentially fatal hepatotoxicity, and should contact the local poison center for reporting and assistance with management of these patients.

Original languageEnglish (US)
Pages (from-to)549-553
Number of pages5
JournalMorbidity and Mortality Weekly Report
Volume66
Issue number21
DOIs
StatePublished - Jun 2 2017

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Mushroom Poisoning
Amanita
Agaricales
control system
Poisons
Eating
intoxication
eating behavior
assistance
public health
contact
Disease Outbreaks
health care
death
cause
human being
Public Health Practice
Antidotes
evaluation
management

ASJC Scopus subject areas

  • Epidemiology
  • Health(social science)
  • Health, Toxicology and Mutagenesis
  • Health Information Management

Cite this

Vo, K. T., Montgomery, M. E., Todd Mitchell, S., Scheerlinck, P. H., Colby, D., Meier, K. H., ... Smollin, C. G. (2017). Amanita phalloides mushroom poisonings - Northern California, December 2016. Morbidity and Mortality Weekly Report, 66(21), 549-553. https://doi.org/10.15585/mmwr.mm6621a1

Amanita phalloides mushroom poisonings - Northern California, December 2016. / Vo, Kathy T.; Montgomery, Martha E.; Todd Mitchell, S.; Scheerlinck, Pieter H.; Colby, Daniel; Meier, Kathryn H.; Kim-Katz, Susan; Anderson, Ilene B.; Offerman, Steven R.; Olson, Kent R.; Smollin, Craig G.

In: Morbidity and Mortality Weekly Report, Vol. 66, No. 21, 02.06.2017, p. 549-553.

Research output: Contribution to journalArticle

Vo, KT, Montgomery, ME, Todd Mitchell, S, Scheerlinck, PH, Colby, D, Meier, KH, Kim-Katz, S, Anderson, IB, Offerman, SR, Olson, KR & Smollin, CG 2017, 'Amanita phalloides mushroom poisonings - Northern California, December 2016', Morbidity and Mortality Weekly Report, vol. 66, no. 21, pp. 549-553. https://doi.org/10.15585/mmwr.mm6621a1
Vo, Kathy T. ; Montgomery, Martha E. ; Todd Mitchell, S. ; Scheerlinck, Pieter H. ; Colby, Daniel ; Meier, Kathryn H. ; Kim-Katz, Susan ; Anderson, Ilene B. ; Offerman, Steven R. ; Olson, Kent R. ; Smollin, Craig G. / Amanita phalloides mushroom poisonings - Northern California, December 2016. In: Morbidity and Mortality Weekly Report. 2017 ; Vol. 66, No. 21. pp. 549-553.
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