Altered cardiac myocyte Ca regulation in heart failure

Research output: Contribution to journalArticle

231 Scopus citations

Abstract

Ca is critical in both the electrical and mechanical properties of cardiac myocytes, and much is known about ionic currents and the normal excitation-contraction coupling process. In heart failure, there are significant alterations in how myocyte Ca is regulated, and these alterations are critical in dictating both contractile dysfunction and certain cardiac arrhythmias that are characteristic of heart failure.

Original languageEnglish (US)
Pages (from-to)380-387
Number of pages8
JournalPhysiology
Volume21
Issue number6
DOIs
StatePublished - Dec 2006
Externally publishedYes

ASJC Scopus subject areas

  • Physiology

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