Abstract
Pre-infection with mouse hepatitis virus (MHV) strains S, 3, or JHM reduced the ability of mice to seroconvert to PVM. Geometric mean antibody titers to PVM among MHV pre-infected mice were lower than those for control mice given only PVM, and dually infected mice seroconverted to PVM later than mice given PVM alone. PVM was not recovered from normally permissive respiratory tract tissues of MHV-S pre-infected mice. Pre-infection of DBA/2 mice with MHV-S compromised the susceptibility of these mice to lethal Sendai virus infection but did not substantially reduce the titers of infectious Sendai virus recovered from the lungs. Serologic responses to Sendai virus and lung Sendai virus titers were similar in Sendai virus-resistant C57BL/6 mice pre-infected or not with MHV-S.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 573-576 |
| Number of pages | 4 |
| Journal | Laboratory animal science Chicago |
| Volume | 34 |
| Issue number | 6 |
| State | Published - Dec 1984 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
Cite this
Alteration of viral respiratory infections of mice by prior infection with mouse hepatitis virus. / Carrano, V. A.; Barthold, Stephen W; Beck, D. S.; Smith, A. L.
In: Laboratory animal science Chicago, Vol. 34, No. 6, 12.1984, p. 573-576.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Alteration of viral respiratory infections of mice by prior infection with mouse hepatitis virus.
AU - Carrano, V. A.
AU - Barthold, Stephen W
AU - Beck, D. S.
AU - Smith, A. L.
PY - 1984/12
Y1 - 1984/12
N2 - Pre-infection with mouse hepatitis virus (MHV) strains S, 3, or JHM reduced the ability of mice to seroconvert to PVM. Geometric mean antibody titers to PVM among MHV pre-infected mice were lower than those for control mice given only PVM, and dually infected mice seroconverted to PVM later than mice given PVM alone. PVM was not recovered from normally permissive respiratory tract tissues of MHV-S pre-infected mice. Pre-infection of DBA/2 mice with MHV-S compromised the susceptibility of these mice to lethal Sendai virus infection but did not substantially reduce the titers of infectious Sendai virus recovered from the lungs. Serologic responses to Sendai virus and lung Sendai virus titers were similar in Sendai virus-resistant C57BL/6 mice pre-infected or not with MHV-S.
AB - Pre-infection with mouse hepatitis virus (MHV) strains S, 3, or JHM reduced the ability of mice to seroconvert to PVM. Geometric mean antibody titers to PVM among MHV pre-infected mice were lower than those for control mice given only PVM, and dually infected mice seroconverted to PVM later than mice given PVM alone. PVM was not recovered from normally permissive respiratory tract tissues of MHV-S pre-infected mice. Pre-infection of DBA/2 mice with MHV-S compromised the susceptibility of these mice to lethal Sendai virus infection but did not substantially reduce the titers of infectious Sendai virus recovered from the lungs. Serologic responses to Sendai virus and lung Sendai virus titers were similar in Sendai virus-resistant C57BL/6 mice pre-infected or not with MHV-S.
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UR - http://www.scopus.com/inward/citedby.url?scp=0021730254&partnerID=8YFLogxK
M3 - Article
C2 - 6097762
AN - SCOPUS:0021730254
VL - 34
SP - 573
EP - 576
JO - Comparative Medicine
JF - Comparative Medicine
SN - 1532-0820
IS - 6
ER -