Allogeneic marrow grafting for treatment of aplastic anemia: a follow up on long term survivors

R. Storb, E. D. Thomas, C. D. Buckner, R. A. Clift, A. Fefer, Leonor P Fernando, E. R. Giblett, F. L. Johnson, P. E. Neiman

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

11 of 24 patients with severe aplastic anemia given marrow grafts from HLA identical siblings between October 1970 and March 1973 are alive with normal marrow function and continued evidence of engraftment 3-5 yr later. Ten have been leading normal lives with no immunosuppressive or other drug therapy since day 100 postgrafting. One has had chronic graft versus host disease of the skin which is now slowly improving with no therapy. He returned to full time employment in the summer of 1975. The long term well being of almost half of the authors' initial patients emphasizes the importance of marrow transplantation for the treatment of severe aplastic anemia.

Original languageEnglish (US)
Pages (from-to)485-490
Number of pages6
JournalBlood
Volume48
Issue number4
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • Hematology

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    Storb, R., Thomas, E. D., Buckner, C. D., Clift, R. A., Fefer, A., Fernando, L. P., Giblett, E. R., Johnson, F. L., & Neiman, P. E. (1976). Allogeneic marrow grafting for treatment of aplastic anemia: a follow up on long term survivors. Blood, 48(4), 485-490.