Aleutian Disease

An Emerging Disease in Free-Ranging Striped Skunks (Mephitis mephitis) From California

E. E B LaDouceur, Mark L Anderson, B. W. Ritchie, P. Ciembor, G. Rimoldi, M. Piazza, D. Pesti, D. L. Clifford, F. Giannitti

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Aleutian disease virus (ADV, Amdovirus, Parvoviridae) primarily infects farmed mustelids (mink and ferrets) but also other fur-bearing animals and humans. Three Aleutian disease (AD) cases have been described in captive striped skunks; however, little is known about the relevance of AD in free-ranging carnivores. This work describes the pathological findings and temporospatial distribution in 7 cases of AD in free-ranging striped skunks. All cases showed neurologic disease and were found in a 46-month period (2010–2013) within a localized geographical region in California. Lesions included multisystemic plasmacytic and lymphocytic inflammation (ie, interstitial nephritis, myocarditis, hepatitis, meningoencephalitis, pneumonia, and splenitis), glomerulonephritis, arteritis with or without fibrinoid necrosis in several organs (ie, kidney, heart, brain, and spleen), splenomegaly, ascites/hydrothorax, and/or encephalomalacia with cerebral microangiopathy. ADV infection was confirmed in all cases by specific polymerase chain reaction and/or in situ hybridization. The results suggest that AD is an emerging disease in free-ranging striped skunks in California.

Original languageEnglish (US)
Pages (from-to)1250-1253
Number of pages4
JournalVeterinary Pathology
Volume52
Issue number6
DOIs
StatePublished - Nov 1 2015

Fingerprint

Mephitidae
Aleutian mink disease
Mephitis mephitis
skunks
emerging diseases
Amdovirus
Parvoviridae
Aleutian mink disease virus
microangiopathy
fur-bearing animals
encephalomalacia
Aleutian Mink Disease Virus
arteritis
glomerulonephritis
splenomegaly
myocarditis
Cerebral Small Vessel Diseases
nephritis
Encephalomalacia
meningoencephalitis

Keywords

  • fibrinoid arteritis
  • infectious diseases
  • Mephitis mephitis
  • nephritis
  • Parvoviridae
  • pathology
  • striped skunk
  • wildlife

ASJC Scopus subject areas

  • veterinary(all)

Cite this

LaDouceur, E. E. B., Anderson, M. L., Ritchie, B. W., Ciembor, P., Rimoldi, G., Piazza, M., ... Giannitti, F. (2015). Aleutian Disease: An Emerging Disease in Free-Ranging Striped Skunks (Mephitis mephitis) From California. Veterinary Pathology, 52(6), 1250-1253. https://doi.org/10.1177/0300985814560234

Aleutian Disease : An Emerging Disease in Free-Ranging Striped Skunks (Mephitis mephitis) From California. / LaDouceur, E. E B; Anderson, Mark L; Ritchie, B. W.; Ciembor, P.; Rimoldi, G.; Piazza, M.; Pesti, D.; Clifford, D. L.; Giannitti, F.

In: Veterinary Pathology, Vol. 52, No. 6, 01.11.2015, p. 1250-1253.

Research output: Contribution to journalArticle

LaDouceur, EEB, Anderson, ML, Ritchie, BW, Ciembor, P, Rimoldi, G, Piazza, M, Pesti, D, Clifford, DL & Giannitti, F 2015, 'Aleutian Disease: An Emerging Disease in Free-Ranging Striped Skunks (Mephitis mephitis) From California', Veterinary Pathology, vol. 52, no. 6, pp. 1250-1253. https://doi.org/10.1177/0300985814560234
LaDouceur, E. E B ; Anderson, Mark L ; Ritchie, B. W. ; Ciembor, P. ; Rimoldi, G. ; Piazza, M. ; Pesti, D. ; Clifford, D. L. ; Giannitti, F. / Aleutian Disease : An Emerging Disease in Free-Ranging Striped Skunks (Mephitis mephitis) From California. In: Veterinary Pathology. 2015 ; Vol. 52, No. 6. pp. 1250-1253.
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