Alcohol use dependence in fragile X syndrome

María J. Salcedo-Arellano, Reymundo Lozano, Flora Tassone, Randi J Hagerman, Wilmar Saldarriaga

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Alcohol use disorders (AUDs) have been reported in a limited number of individuals with cognitive impairment but rarely in those with fragile X syndrome (FXS). However, in Colombia, culturally, alcohol consumption is very common. Here, we report eight cases of patients with FXS who have frequent alcohol consumption in Ricaurte, Colombia. Some of these patients have also used tobacco and illegal substances, including cocaine, which use has not been previously reported in those with FXS. Alcohol and substance use dependence is associated with exacerbation of their behavioral problems, such as increased impulsivity and aggression, as well as of medical problems such as an increased frequency of seizures.

Original languageEnglish (US)
Pages (from-to)207-213
Number of pages7
JournalIntractable and Rare Diseases Research
Issue number3
StatePublished - 2016


  • Alcohol use disorders
  • Fragile X syndrome

ASJC Scopus subject areas

  • Medicine(all)


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