Aging, aerobic activity and interhemispheric communication

Keith M. McGregor, Kenneth M. Heilman, Joe R. Nocera, Carolynn Patten, Todd M. Manini, Bruce Crosson, Andrew J. Butler

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Recent studies have shown that during unimanual motor tasks, aging adults show bilateral recruitment of primary motor cortex (M1), while younger adults show a suppression of the ipsilateral motor cortex. Additional work has indicated that increased bilateral M1 recruitment in older adults may be deleterious when performing some motor tasks. However, higher levels of physical fitness are associated with improved dexterity and fitness may mitigate the loss of both inhibitory and excitatory communication in aging adults. The goal of this study was to assess dexterity and interhemispheric motor communication in physically fit and sedentary middle-age (40-60 years) right handed participants using tests of hand deftness and transcranial magnetic stimulation (TMS). To behaviorally assess the influence of interhemispheric communication on motor performance, participants also perform the coin rotation deftness task while maintaining pinch force with the opposite hand (bimanual condition). We correlated these behavioral measures with the ipsilateral silent period using TMS to assess interhemispheric inhibition. Our results show that the middle-aged adults who were physically fit had better dexterity of their right hand (finger tapping and peg-board). When performing the coin rotation task the fit group had no between hand differences, but the sedentary group's left hand performance was inferior to the their right hand. We found that better dexterity correlated with ipsilateral silent period duration (greater inhibition) thereby supporting the postulate that fitness improves interhemispheric motor communication.

Original languageEnglish (US)
Pages (from-to)634-648
Number of pages15
JournalBrain Sciences
Volume2
Issue number4
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

Fingerprint

Hand
Communication
Numismatics
Transcranial Magnetic Stimulation
Motor Cortex
Physical Fitness
Fingers
Young Adult
Inhibition (Psychology)

Keywords

  • Aging
  • Dexterity
  • Interhemispheric communication
  • Physical fitness
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

McGregor, K. M., Heilman, K. M., Nocera, J. R., Patten, C., Manini, T. M., Crosson, B., & Butler, A. J. (2012). Aging, aerobic activity and interhemispheric communication. Brain Sciences, 2(4), 634-648. https://doi.org/10.3390/brainsci2040634

Aging, aerobic activity and interhemispheric communication. / McGregor, Keith M.; Heilman, Kenneth M.; Nocera, Joe R.; Patten, Carolynn; Manini, Todd M.; Crosson, Bruce; Butler, Andrew J.

In: Brain Sciences, Vol. 2, No. 4, 01.01.2012, p. 634-648.

Research output: Contribution to journalArticle

McGregor, KM, Heilman, KM, Nocera, JR, Patten, C, Manini, TM, Crosson, B & Butler, AJ 2012, 'Aging, aerobic activity and interhemispheric communication', Brain Sciences, vol. 2, no. 4, pp. 634-648. https://doi.org/10.3390/brainsci2040634
McGregor KM, Heilman KM, Nocera JR, Patten C, Manini TM, Crosson B et al. Aging, aerobic activity and interhemispheric communication. Brain Sciences. 2012 Jan 1;2(4):634-648. https://doi.org/10.3390/brainsci2040634
McGregor, Keith M. ; Heilman, Kenneth M. ; Nocera, Joe R. ; Patten, Carolynn ; Manini, Todd M. ; Crosson, Bruce ; Butler, Andrew J. / Aging, aerobic activity and interhemispheric communication. In: Brain Sciences. 2012 ; Vol. 2, No. 4. pp. 634-648.
@article{c41f0ea1e31f40edac9bea711ca6a633,
title = "Aging, aerobic activity and interhemispheric communication",
abstract = "Recent studies have shown that during unimanual motor tasks, aging adults show bilateral recruitment of primary motor cortex (M1), while younger adults show a suppression of the ipsilateral motor cortex. Additional work has indicated that increased bilateral M1 recruitment in older adults may be deleterious when performing some motor tasks. However, higher levels of physical fitness are associated with improved dexterity and fitness may mitigate the loss of both inhibitory and excitatory communication in aging adults. The goal of this study was to assess dexterity and interhemispheric motor communication in physically fit and sedentary middle-age (40-60 years) right handed participants using tests of hand deftness and transcranial magnetic stimulation (TMS). To behaviorally assess the influence of interhemispheric communication on motor performance, participants also perform the coin rotation deftness task while maintaining pinch force with the opposite hand (bimanual condition). We correlated these behavioral measures with the ipsilateral silent period using TMS to assess interhemispheric inhibition. Our results show that the middle-aged adults who were physically fit had better dexterity of their right hand (finger tapping and peg-board). When performing the coin rotation task the fit group had no between hand differences, but the sedentary group's left hand performance was inferior to the their right hand. We found that better dexterity correlated with ipsilateral silent period duration (greater inhibition) thereby supporting the postulate that fitness improves interhemispheric motor communication.",
keywords = "Aging, Dexterity, Interhemispheric communication, Physical fitness, Transcranial magnetic stimulation",
author = "McGregor, {Keith M.} and Heilman, {Kenneth M.} and Nocera, {Joe R.} and Carolynn Patten and Manini, {Todd M.} and Bruce Crosson and Butler, {Andrew J.}",
year = "2012",
month = "1",
day = "1",
doi = "10.3390/brainsci2040634",
language = "English (US)",
volume = "2",
pages = "634--648",
journal = "Brain Sciences",
issn = "2076-3425",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "4",

}

TY - JOUR

T1 - Aging, aerobic activity and interhemispheric communication

AU - McGregor, Keith M.

AU - Heilman, Kenneth M.

AU - Nocera, Joe R.

AU - Patten, Carolynn

AU - Manini, Todd M.

AU - Crosson, Bruce

AU - Butler, Andrew J.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Recent studies have shown that during unimanual motor tasks, aging adults show bilateral recruitment of primary motor cortex (M1), while younger adults show a suppression of the ipsilateral motor cortex. Additional work has indicated that increased bilateral M1 recruitment in older adults may be deleterious when performing some motor tasks. However, higher levels of physical fitness are associated with improved dexterity and fitness may mitigate the loss of both inhibitory and excitatory communication in aging adults. The goal of this study was to assess dexterity and interhemispheric motor communication in physically fit and sedentary middle-age (40-60 years) right handed participants using tests of hand deftness and transcranial magnetic stimulation (TMS). To behaviorally assess the influence of interhemispheric communication on motor performance, participants also perform the coin rotation deftness task while maintaining pinch force with the opposite hand (bimanual condition). We correlated these behavioral measures with the ipsilateral silent period using TMS to assess interhemispheric inhibition. Our results show that the middle-aged adults who were physically fit had better dexterity of their right hand (finger tapping and peg-board). When performing the coin rotation task the fit group had no between hand differences, but the sedentary group's left hand performance was inferior to the their right hand. We found that better dexterity correlated with ipsilateral silent period duration (greater inhibition) thereby supporting the postulate that fitness improves interhemispheric motor communication.

AB - Recent studies have shown that during unimanual motor tasks, aging adults show bilateral recruitment of primary motor cortex (M1), while younger adults show a suppression of the ipsilateral motor cortex. Additional work has indicated that increased bilateral M1 recruitment in older adults may be deleterious when performing some motor tasks. However, higher levels of physical fitness are associated with improved dexterity and fitness may mitigate the loss of both inhibitory and excitatory communication in aging adults. The goal of this study was to assess dexterity and interhemispheric motor communication in physically fit and sedentary middle-age (40-60 years) right handed participants using tests of hand deftness and transcranial magnetic stimulation (TMS). To behaviorally assess the influence of interhemispheric communication on motor performance, participants also perform the coin rotation deftness task while maintaining pinch force with the opposite hand (bimanual condition). We correlated these behavioral measures with the ipsilateral silent period using TMS to assess interhemispheric inhibition. Our results show that the middle-aged adults who were physically fit had better dexterity of their right hand (finger tapping and peg-board). When performing the coin rotation task the fit group had no between hand differences, but the sedentary group's left hand performance was inferior to the their right hand. We found that better dexterity correlated with ipsilateral silent period duration (greater inhibition) thereby supporting the postulate that fitness improves interhemispheric motor communication.

KW - Aging

KW - Dexterity

KW - Interhemispheric communication

KW - Physical fitness

KW - Transcranial magnetic stimulation

UR - http://www.scopus.com/inward/record.url?scp=84895804219&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84895804219&partnerID=8YFLogxK

U2 - 10.3390/brainsci2040634

DO - 10.3390/brainsci2040634

M3 - Article

VL - 2

SP - 634

EP - 648

JO - Brain Sciences

JF - Brain Sciences

SN - 2076-3425

IS - 4

ER -