Age, sex and reproductive status alter the severity of anorexia in zinc deficient rats

Jerrolynn C. Kawamoto, Thomas W. Castonguay, Carl L Keen, Judith S. Stern, Lucille S. Hurley

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Food intake and body weight gain in rats fed a zinc-deficient diet are reported. The severity of zinc deficiency-induced anorexia was observed to be dependent upon the age, sex and reproductive status of the animal. Rapidly growing rats such as weanlings, adult males, or ovariectomized females demonstrated more rapid induction of anorexia and more severe effects on cumulative food intake and body weight gain when fed zinc-deficient diets than did slowly growing (nonpregnant female adult) rats given the same diet. These results suggest that feeding in zinc-deficient animals is not regulated by dietary zinc concentration alone, but rather is mediated by one or several as yet undefined factors.

Original languageEnglish (US)
Pages (from-to)485-493
Number of pages9
JournalPhysiology and Behavior
Volume38
Issue number4
DOIs
StatePublished - 1986

Keywords

  • Anorexia
  • Estradiol
  • Food intake
  • Hormones
  • Zinc

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

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    Kawamoto, J. C., Castonguay, T. W., Keen, C. L., Stern, J. S., & Hurley, L. S. (1986). Age, sex and reproductive status alter the severity of anorexia in zinc deficient rats. Physiology and Behavior, 38(4), 485-493. https://doi.org/10.1016/0031-9384(86)90415-4