Age-related morphometry of equine calcified cartilage

M. J. Martinelli, J. Eurell, C. M. Les, David P Fyhrie, D. Bennett

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Although there are many studies in the equine literature focused on articular diseases and the aetiology of osteoarthritis, few have concentrated on normal articular structures and how they change with age. The objective of this investigation was to study the thickness and morphology of the calcified cartilage layer of the distal metacarpus over a range of ages. A parasagittal slab of bone was sectioned from the region of sesamoid contact on the medial condyle of the metacarpi from 34 horses. The slab of bone was preserved, dehydrated and embedded, undecalcified, in methylmethacrylate and then stained with toluidine blue. Six repeatable fields of interest from the distal aspect of each metacarpus were digitised and examined to determine the morphology of the calcified cartilage layer. The thickness of the calcified cartilage, range 88-426 μm, was estimated using a method of integration. The results indicate an age-related influence on the thickness of the calcified cartilage layer, generally increased in older horses. While this finding is significant, perhaps more importantly a positional relationship was also identified, indicating that pressures endured by different regions within a joint may dictate morphological development of the tissues. This study has begun to lay the groundwork to determine whether the calcified layer of the hyaline cartilage could be involved in the development of osteoarthritis.

Original languageEnglish (US)
Pages (from-to)274-278
Number of pages5
JournalEquine Veterinary Journal
Volume34
Issue number3
StatePublished - May 2002
Externally publishedYes

Fingerprint

Metacarpus
morphometry
cartilage
Horses
Cartilage
metacarpus
horses
Joints
Bone and Bones
Osteoarthritis
slabs
osteoarthritis
Methylmethacrylate
Hyaline Cartilage
Tolonium Chloride
bones
toluidine blue
joints (animal)
etiology
Pressure

Keywords

  • Articular cartilage
  • Calcified cartilage
  • Horse
  • Osteoarthritis

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Martinelli, M. J., Eurell, J., Les, C. M., Fyhrie, D. P., & Bennett, D. (2002). Age-related morphometry of equine calcified cartilage. Equine Veterinary Journal, 34(3), 274-278.

Age-related morphometry of equine calcified cartilage. / Martinelli, M. J.; Eurell, J.; Les, C. M.; Fyhrie, David P; Bennett, D.

In: Equine Veterinary Journal, Vol. 34, No. 3, 05.2002, p. 274-278.

Research output: Contribution to journalArticle

Martinelli, MJ, Eurell, J, Les, CM, Fyhrie, DP & Bennett, D 2002, 'Age-related morphometry of equine calcified cartilage', Equine Veterinary Journal, vol. 34, no. 3, pp. 274-278.
Martinelli MJ, Eurell J, Les CM, Fyhrie DP, Bennett D. Age-related morphometry of equine calcified cartilage. Equine Veterinary Journal. 2002 May;34(3):274-278.
Martinelli, M. J. ; Eurell, J. ; Les, C. M. ; Fyhrie, David P ; Bennett, D. / Age-related morphometry of equine calcified cartilage. In: Equine Veterinary Journal. 2002 ; Vol. 34, No. 3. pp. 274-278.
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